电化学有氧氧化断裂烷基芳烃中的(sp)C-C(sp)/H 键。
Electrochemical Aerobic Oxidative Cleavage of (sp)C-C(sp)/H Bonds in Alkylarenes.
机构信息
Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Institute of Molecular Sciences, University of Bordeaux, 351 Cours de la Libération, 33405 Talence, France.
出版信息
J Org Chem. 2022 Mar 4;87(5):3286-3295. doi: 10.1021/acs.joc.1c02947. Epub 2022 Feb 21.
An electrochemistry-promoted oxidative cleavage of (sp)C-C(sp)/H bonds in alkylarenes was developed. Various aryl alkanes can be smoothly converted into ketones/aldehydes under aerobic conditions using a user-friendly undivided cell setup. The features of air as oxidant, scalability, and mild conditions make them attractive in synthetic organic chemistry.
发展了一种电化学促进的芳基烷基 C(sp)-C(sp)/H 键的氧化裂解反应。使用用户友好的不分流池装置，在有氧条件下，各种芳基烷烃可以顺利转化为酮/醛。空气作为氧化剂、可扩展性和温和的条件是它们在有机合成化学中具有吸引力的特点。
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