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分析儿童 Ahmed 青光眼阀(FP8)在高龄人群中的疗效和安全性。

Analysis of Efficacy and Safety of Pediatric Ahmed Glaucoma Valve (FP8) in Advanced Age Populations.

机构信息

Department of Ophthalmology and Visual Sciences, Faculty of Science, University of Alberta, Vancouver, BC.

Departments of Surgery.

出版信息

J Glaucoma. 2021 Feb 1;30(2):164-169. doi: 10.1097/IJG.0000000000001701.

Abstract

PRECIS

The FP8 glaucoma valve was demonstrated to be reasonably safe with reliable results in an advanced age patient population.

PURPOSE

As life expectancy increases, a growing number of patients with glaucoma are of an advanced age. There are little to no data looking at glaucoma surgical treatment options in patients over the age of 85. Our study describes the safety and efficacy of the FP8 Ahmed glaucoma valve in this patient population.

MATERIALS AND METHODS

This was a retrospective study of patients over 85 years of age undergoing FP8 Ahmed glaucoma valve implantation. Preoperative age, sex, intraocular pressure (IOP), and number of glaucoma medications were recorded. Primary outcome variables were IOP and number of medications. Secondary outcome variables included any intraoperative or postoperative complications.

RESULTS

Mean IOP preoperatively was 26 mm Hg on an average of 3 glaucoma medications (n=56). IOP was significantly reduced at all time points in follow-up for an overall reduction of 42% at 1 year and 46% at 2 years. Mean IOP at 1 year follow-up was 15 mm Hg and 14 mm Hg at 2 years follow-up. Glaucoma medications were reduced from a mean of 3 preoperatively to 2 postoperatively.

CONCLUSIONS

Implantation of an FP8 Ahmed glaucoma valve is a relatively safe procedure to achieve satisfactory IOP and decreased reliance on glaucoma medications in an advanced age population.

摘要

摘要

FP8 青光眼引流阀在高龄患者人群中表现出合理的安全性和可靠的结果。

目的

随着预期寿命的延长,越来越多的青光眼患者年龄较大。对于 85 岁以上的患者,几乎没有关于青光眼手术治疗选择的数据。我们的研究描述了 FP8 Ahmed 青光眼引流阀在这一患者群体中的安全性和有效性。

材料和方法

这是一项回顾性研究,研究对象为接受 FP8 Ahmed 青光眼引流阀植入术的 85 岁以上患者。记录术前年龄、性别、眼内压(IOP)和青光眼药物数量。主要观察变量为 IOP 和药物数量。次要观察变量包括任何术中或术后并发症。

结果

平均术前 IOP 为 26mmHg,平均使用 3 种降眼压药物(n=56)。在随访的所有时间点,IOP 均显著降低,随访 1 年时总体降低 42%,随访 2 年时总体降低 46%。1 年随访时的平均 IOP 为 15mmHg,2 年随访时的平均 IOP 为 14mmHg。术前平均使用 3 种降眼压药物,术后减少至 2 种。

结论

在高龄人群中,植入 FP8 Ahmed 青光眼引流阀是一种相对安全的手术方法,可以达到满意的 IOP 并减少对青光眼药物的依赖。

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