Werner Mark, Byun Stephanie, Shin Rebecca, Freeman Katherine
Department of Glaucoma, Delray Eye Associates, Delray Beach, Florida, United States.
Department of Medicine, Charles E Schmidt/Florida Atlantic University College of Medicine, Boca Raton, Florida, United States.
J Curr Glaucoma Pract. 2024 Oct-Dec;18(4):162-170. doi: 10.5005/jp-journals-10078-1454. Epub 2025 Jan 20.
To compare outcomes of glaucoma tube shunt surgery in patients aged 85 years and older to younger adults.
Medical records were reviewed involving 207 consecutive tube shunt surgeries performed by one surgeon between 2013 and 2019. Baseline characteristics between group A (adults aged <85) and group B (aged ≥85) were compared. Changes from baseline to 12 months were compared between groups.
One-year follow-up was completed for 80 of 125 eyes (group A) and 49 of 82 eyes (group B). Intraocular pressure (IOP) and number of medications were statistically significantly reduced at 12 months, with no significant difference between groups (group A: 33.1 ± 11.2 → 13.8 ± 4.5 mm Hg, group B: IOP 33.6 ± 10.2 → 14.0 ± 4.3 mm Hg; = 0.7168; group A: 3.2 ± 1.2 → 1.6 ± 1.3 meds, group B: 3.2 ± 1.1 → 1.8 ± 1.4 meds; = 0.8404). Success rate was 109/128 (85.1%) overall, with no significant difference between groups ( = 0.2625). LogMAR visual acuity (VA) significantly worsened in group B only (group A: 0.68 ± 0.59 preop → 0.67 ± 0.58 postop; group B: 0.79 ± 0.60 preop → 0.98 ± 0.73 postop; = 0.0006). More older patients lost ≥0.25 logMAR VA (group A: 11/80 = 14% vs group B: 17/49 = 35%; = 0.0051).
For advanced-age patients, tube shunt surgery provides good intraocular pressure control, with a higher, though acceptable, risk of loss of VA.
Tube shunts may be undertaken in patients of advanced age at high risk of vision loss from glaucoma.
Werner M, Byun S, Shin R, . Intermediate-term Outcomes of Glaucoma Drainage Device Implantation in Adults of Advanced Age. J Curr Glaucoma Pract 2024;18(4):162-170.
比较85岁及以上老年患者与年轻成人青光眼引流管分流手术的效果。
回顾了2013年至2019年间由一名外科医生连续进行的207例引流管分流手术的病历。比较A组(年龄<85岁的成人)和B组(年龄≥85岁)的基线特征。比较两组从基线到12个月的变化。
A组125只眼中的80只和B组82只眼中的49只完成了一年的随访。12个月时眼压(IOP)和用药数量在统计学上显著降低,两组之间无显著差异(A组:33.1±11.2→13.8±4.5 mmHg,B组:眼压为33.6±10.2→14.0±4.3 mmHg;P = 0.7168;A组:3.2±1.2→1.6±1.3种药物,B组:3.2±1.1→1.8±1.4种药物;P = 0.8404)。总体成功率为109/128(85.1%),两组之间无显著差异(P = 0.2625)。仅B组的对数最小分辨角视力(VA)显著恶化(A组:术前0.68±0.59→术后0.67±0.58;B组:术前0.79±0.60→术后0.98±0.73;P = 0.0006)。更多老年患者的VA损失≥0.25对数最小分辨角(A组:11/80 = 14% vs B组:17/49 = 35%;P = 0.0051)。
对于高龄患者,引流管分流手术可提供良好的眼压控制,但视力丧失风险较高,不过仍在可接受范围内。
对于因青光眼有高视力丧失风险的高龄患者可进行引流管分流手术。
Werner M, Byun S, Shin R, 等。高龄成人青光眼引流装置植入的中期结果。《当代青光眼实践杂志》2024;18(4):162 - 170。