Suppr超能文献

高龄成人青光眼引流装置植入术的中期结果

Intermediate-term Outcomes of Glaucoma Drainage Device Implantation in Adults of Advanced Age.

作者信息

Werner Mark, Byun Stephanie, Shin Rebecca, Freeman Katherine

机构信息

Department of Glaucoma, Delray Eye Associates, Delray Beach, Florida, United States.

Department of Medicine, Charles E Schmidt/Florida Atlantic University College of Medicine, Boca Raton, Florida, United States.

出版信息

J Curr Glaucoma Pract. 2024 Oct-Dec;18(4):162-170. doi: 10.5005/jp-journals-10078-1454. Epub 2025 Jan 20.

Abstract

AIM AND BACKGROUND

To compare outcomes of glaucoma tube shunt surgery in patients aged 85 years and older to younger adults.

METHODS

Medical records were reviewed involving 207 consecutive tube shunt surgeries performed by one surgeon between 2013 and 2019. Baseline characteristics between group A (adults aged <85) and group B (aged ≥85) were compared. Changes from baseline to 12 months were compared between groups.

RESULTS

One-year follow-up was completed for 80 of 125 eyes (group A) and 49 of 82 eyes (group B). Intraocular pressure (IOP) and number of medications were statistically significantly reduced at 12 months, with no significant difference between groups (group A: 33.1 ± 11.2 → 13.8 ± 4.5 mm Hg, group B: IOP 33.6 ± 10.2 → 14.0 ± 4.3 mm Hg; = 0.7168; group A: 3.2 ± 1.2 → 1.6 ± 1.3 meds, group B: 3.2 ± 1.1 → 1.8 ± 1.4 meds; = 0.8404). Success rate was 109/128 (85.1%) overall, with no significant difference between groups ( = 0.2625). LogMAR visual acuity (VA) significantly worsened in group B only (group A: 0.68 ± 0.59 preop → 0.67 ± 0.58 postop; group B: 0.79 ± 0.60 preop → 0.98 ± 0.73 postop; = 0.0006). More older patients lost ≥0.25 logMAR VA (group A: 11/80 = 14% vs group B: 17/49 = 35%; = 0.0051).

CONCLUSION

For advanced-age patients, tube shunt surgery provides good intraocular pressure control, with a higher, though acceptable, risk of loss of VA.

CLINICAL SIGNIFICANCE

Tube shunts may be undertaken in patients of advanced age at high risk of vision loss from glaucoma.

HOW TO CITE THIS ARTICLE

Werner M, Byun S, Shin R, . Intermediate-term Outcomes of Glaucoma Drainage Device Implantation in Adults of Advanced Age. J Curr Glaucoma Pract 2024;18(4):162-170.

摘要

目的与背景

比较85岁及以上老年患者与年轻成人青光眼引流管分流手术的效果。

方法

回顾了2013年至2019年间由一名外科医生连续进行的207例引流管分流手术的病历。比较A组(年龄<85岁的成人)和B组(年龄≥85岁)的基线特征。比较两组从基线到12个月的变化。

结果

A组125只眼中的80只和B组82只眼中的49只完成了一年的随访。12个月时眼压(IOP)和用药数量在统计学上显著降低,两组之间无显著差异(A组:33.1±11.2→13.8±4.5 mmHg,B组:眼压为33.6±10.2→14.0±4.3 mmHg;P = 0.7168;A组:3.2±1.2→1.6±1.3种药物,B组:3.2±1.1→1.8±1.4种药物;P = 0.8404)。总体成功率为109/128(85.1%),两组之间无显著差异(P = 0.2625)。仅B组的对数最小分辨角视力(VA)显著恶化(A组:术前0.68±0.59→术后0.67±0.58;B组:术前0.79±0.60→术后0.98±0.73;P = 0.0006)。更多老年患者的VA损失≥0.25对数最小分辨角(A组:11/80 = 14% vs B组:17/49 = 35%;P = 0.0051)。

结论

对于高龄患者,引流管分流手术可提供良好的眼压控制,但视力丧失风险较高,不过仍在可接受范围内。

临床意义

对于因青光眼有高视力丧失风险的高龄患者可进行引流管分流手术。

如何引用本文

Werner M, Byun S, Shin R, 等。高龄成人青光眼引流装置植入的中期结果。《当代青光眼实践杂志》2024;18(4):162 - 170。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/852f/11915357/abb6aded9b29/jocgp-18-162-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验