Dermatologic Clinic, "Sapienza" University of Rome, Rome, Italy.
Clin Ter. 2021 May 5;172(3):190-192. doi: 10.7417/CT.2021.2311.
Madelung's disease is a rare syndrome characterized by the pre-sence of multiple masses of unencapsulated adipose tissue, symme-trically distributed throughout different regions. It predominantly affects middle-aged men of Mediterranean origin with a history of alcoholism. The pathogenesis is still unknown. Diagnosis is essentially established through clinical history and physical examination. We report two cases for their unusual presentation and to emphasize the importance of early diagnosis.
马德隆氏病是一种罕见的综合征,其特征是存在多个未被包膜的脂肪组织肿块,对称分布于不同区域。它主要影响来自地中海地区有酗酒史的中年男性。其发病机制尚不清楚。诊断主要通过临床病史和体格检查确定。我们报告两例病例,因其表现不典型,故强调早期诊断的重要性。