托珠单抗联合地塞米松的成本效益治疗可降低 COVID-19 死亡率。
Combination Therapy With Tocilizumab and Dexamethasone Cost-Effectively Reduces Coronavirus Disease 2019 Mortality.
机构信息
Section of Infectious Diseases, Department of Internal Medicine, School of Medicine, Boston University, Boston, Massachusetts, USA.
出版信息
Clin Infect Dis. 2021 Dec 6;73(11):2116-2118. doi: 10.1093/cid/ciab409.
Abstract
Recent randomized trials suggest that interleukin-6 inhibitors reduce mortality due to severe coronavirus disease 2019. Using a decision tree model, we found that tocilizumab is cost-effective with an estimated incremental cost-effectiveness ratio of $16 520 per quality-adjusted life year gained (95% credible interval, 10 760-51 530).
摘要
最近的随机临床试验表明，白细胞介素-6 抑制剂可降低因严重 2019 年冠状病毒病导致的死亡率。我们使用决策树模型发现，托珠单抗具有成本效益，估计每获得一个质量调整生命年的增量成本效益比为 16520 美元（95%可信区间为 10760-51530）。
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