Lee Guk Jin, Gwak Ji Hyun, Kim Myoung Sim, Lee Mi Yeong, Kim Seo Ree, Chun Sang Hoon, Jin Jong Youl
Division of Hematology/Oncology, Department of Internal Medicine, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Hospice Unit, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Palliat Support Care. 2021 Oct;19(5):547-551. doi: 10.1017/S1478951520001248.
The accurate estimation of expected survival in terminal cancer patients is important. The palliative performance scale (PPS) is an important factor in predicting survival of hospice patients. The purpose of this study was to examine how initial status of PPS and changes in PPS affect the survival of hospice patients in Korea.
We retrospectively examined 315 patients who were admitted to our hospice unit between January 2017 and December 2018. The patients were divided based on the PPS of ≥50% (group A) and ≤40% (group B). We performed survival analysis for factors associated with the length of survival (LOS) in group A. Based on the hospice team's weekly evaluation of PPS, we examined the effect of initial levels and changes in group A on the prognosis of patients who survived for 2 weeks or more.
At the time of admission to hospice, 265 (84.1%) patients were PPS ≥50%, and 50 (15.9%) were PPS ≤40%. The median LOS of PPS ≥50% and PPS ≤40% were 15 (2-158 days) and 9 (2-43 days), respectively. Male, gastrointestinal cancer, and lower initial PPS all predicted poor prognosis in group A. Male, gastrointestinal cancer, and a PPS change of 10% or greater, compared with initial status 1 week and 2 weeks of hospitalization, were all predictors of poor prognosis in group A patients who survived for 2 weeks or longer.
Our research demonstrates the significance of PPS change at 1 week and 2 weeks, suggesting the importance of evaluating not only initial PPS but also change in PPS.
准确估计晚期癌症患者的预期生存期很重要。姑息治疗表现量表(PPS)是预测临终关怀患者生存期的一个重要因素。本研究的目的是探讨PPS的初始状态及PPS的变化如何影响韩国临终关怀患者的生存期。
我们回顾性研究了2017年1月至2018年12月期间入住我们临终关怀病房的315例患者。患者根据PPS≥50%(A组)和≤40%(B组)进行分组。我们对A组中与生存时长(LOS)相关的因素进行了生存分析。基于临终关怀团队对PPS的每周评估,我们研究了A组的初始水平及变化对存活2周或更长时间患者预后的影响。
临终关怀入院时,265例(84.1%)患者PPS≥50%,50例(15.9%)患者PPS≤40%。PPS≥50%和PPS≤40%的中位LOS分别为15天(2 - 158天)和9天(2 - 43天)。男性、胃肠道癌以及较低的初始PPS均预示A组预后不良。与住院1周和2周时的初始状态相比,男性、胃肠道癌以及PPS变化10%或更大,均是存活2周或更长时间的A组患者预后不良的预测因素。
我们的研究证明了1周和2周时PPS变化的意义,表明不仅评估初始PPS而且评估PPS变化的重要性。