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肝外伤:影响预后的危险因素。

Hepatic trauma: risk factors influencing outcome.

作者信息

Prêtre R, Mentha G, Huber O, Meyer P, Vogel J, Rohner A

机构信息

Département de Chirurgie, Hôpital Cantonal Universitaire, Geneva, Switzerland.

出版信息

Br J Surg. 1988 Jun;75(6):520-4. doi: 10.1002/bjs.1800750606.

Abstract

This retrospective study analyses the fate and associated risk factors of 99 patients who underwent laparotomy for hepatic trauma from 1977 to 1986. Blunt trauma (88 patients) and stab wounds (7 patients) had mortality rates of 36 and 14 per cent respectively. The overall death rate was 35 per cent. Multiple trauma patients had a significantly higher mortality for each additional system that was seriously injured. Pre-operative shock raised the mortality from 20 to 58 per cent (P less than 0.001). For patients over 50 years of age, the mortality rate increased from 30 (younger patients) to 63 per cent (P = 0.028). Minor hepatic wounds required relatively simple surgical measures in 60 patients, yet 13 died (22 per cent) of other causes. More sophisticated surgical management was applied to 27 major hepatic lesions, with 10 deaths (37 per cent). Twelve patients (seven with minor and five with major hepatic wounds) died before surgical treatment of the liver injury could be undertaken. The overall mortality rate of major hepatic wounds was 47 per cent and for minor wounds 30 per cent. However, the difference was not significant (P = 0.152). Resection was resorted to in 15 patients, 5 of whom subsequently died (33 per cent). Classical hepatic lobectomy led to 4 deaths (50 per cent). Among the 35 deaths, 6 were due to the hepatic trauma itself (5 exsanguinations and 1 intra-abdominal sepsis). Isolated hepatic injury was fatal in three patients. We believe that conservative surgical measures should be used whenever possible in patients with hepatic trauma, especially when risk factors are encountered.

摘要

这项回顾性研究分析了1977年至1986年间99例因肝外伤接受剖腹手术患者的转归及相关危险因素。钝性创伤(88例患者)和刺伤(7例患者)的死亡率分别为36%和14%。总体死亡率为35%。多发伤患者每增加一个严重受损的系统,死亡率显著升高。术前休克使死亡率从20%升至58%(P<0.001)。50岁以上患者的死亡率从30%(较年轻患者)升至63%(P = 0.028)。60例轻度肝损伤患者需相对简单的手术措施,但13例(22%)死于其他原因。27例严重肝损伤采用了更复杂的手术处理,10例死亡(37%)。12例患者(7例轻度肝损伤和5例严重肝损伤)在进行肝损伤手术治疗前死亡。严重肝损伤的总体死亡率为47%,轻度肝损伤为30%。然而,差异无统计学意义(P = 0.152)。15例患者接受了肝切除术,其中5例随后死亡(33%)。经典肝叶切除术导致4例死亡(50%)。35例死亡病例中,6例死于肝外伤本身(5例失血性休克和1例腹腔内感染)。3例患者孤立性肝损伤致死。我们认为,肝外伤患者应尽可能采用保守手术措施,尤其是存在危险因素时。

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