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Carbohydrates, insulin, and obesity.

作者信息

Speakman John R, Hall Kevin D

机构信息

Center for Energy Metabolism and Reproduction, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.

State Key Lab of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.

出版信息

Science. 2021 May 7;372(6542):577-578. doi: 10.1126/science.aav0448.

DOI:10.1126/science.aav0448
PMID:33958466
Abstract
摘要

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Carbohydrates, insulin, and obesity.碳水化合物、胰岛素与肥胖
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Influence of diet on the metabolic syndrome of obesity.饮食对肥胖代谢综合征的影响。
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Obesity, islet function and diabetes mellitus.肥胖、胰岛功能与糖尿病
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Effect of dietary carbohydrate source on the development of obesity in agouti transgenic mice.膳食碳水化合物来源对刺豚鼠转基因小鼠肥胖症发展的影响。
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Lipogenesis and obesity in energy storage.能量储存中的脂肪生成与肥胖
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The Banting Memorial Lecture 1971. Physiology of insulin in man.1971年班廷纪念讲座。人类胰岛素生理学
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Glucose metabolism and the response to insulin by human adipose tissue in spontaneous and experimental obesity. Effects of dietary composition and adipose cell size.自发性和实验性肥胖状态下人体脂肪组织的葡萄糖代谢及对胰岛素的反应。饮食组成和脂肪细胞大小的影响。
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Targetted inhibition of CD74 attenuates adipose COX-2-MIF-mediated M1 macrophage polarization and retards obesity-related adipose tissue inflammation and insulin resistance.靶向抑制 CD74 可减弱脂肪组织 COX-2-MIF 介导的 M1 巨噬细胞极化，延缓肥胖相关的脂肪组织炎症和胰岛素抵抗。
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All obesity is not created equal.并非所有肥胖都是一样的。
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