Langston Cathy, Gordon Daniel
The Ohio State University College of Veterinary Medicine, Columbus, OH, United States.
Front Vet Sci. 2021 Apr 20;8:659960. doi: 10.3389/fvets.2021.659960. eCollection 2021.
Intravenous fluid therapy has long been the mainstay of treatment of kidney disease, including acute kidney injury and uremic crisis associated with chronic kidney disease. Careful management of fluid dose is critical, as animals with kidney disease may have marked derangements in their ability to regulate fluid homeostasis and acid-base status. Understanding of the physiology of renal fluid handling is necessary, along with repeated attention to parameters of fluid status, electrolytes, and acid-base balance, to achieve optimal hydration status and avoid further damage or decrease in function from dehydration or overhydration.
静脉输液疗法长期以来一直是肾脏疾病治疗的主要手段,包括急性肾损伤和与慢性肾脏病相关的尿毒症危象。仔细管理输液剂量至关重要,因为患有肾脏疾病的动物在调节液体平衡和酸碱状态的能力方面可能有明显紊乱。了解肾脏液体处理的生理学知识很有必要,同时要反复关注液体状态、电解质和酸碱平衡的参数,以实现最佳的水合状态,避免因脱水或水合过度导致进一步损伤或功能下降。