Engineering Research Center of Micro-nano Optoelectronic Materials and Devices, Ministry of Education, Fujian Key Laboratory of Semiconductor Materials and Applications, CI Center for OSED, Department of Physics, Jiujiang Research Institute, Xiamen University, Xiamen 361005, China.
Nanoscale. 2021 May 20;13(19):8707-8721. doi: 10.1039/d1nr01255j.
Phototreatment is at the leading edge of a research hot topic as a driving force for structural transformation, spectral and electromagnetism improvements, and the functional performance of nanomaterials. Light irradiation can excite surface plasmons in noble metal nanoparticles, create electron-hole pairs, and produce charge transfer in semiconductor substrates, which have led to it being widely used in surface-enhanced Raman spectroscopy (SERS) for life sciences, environmental protection, and biological analysis. Photo-induced enhanced Raman spectroscopy (PIERS) is a new technology developed on the basis of traditional SERS and has proven to be an efficient way to resolve several critical challenges thanks to its incomparable superiority for incontiguous operation, efficient charge separation and enrichment, and a large signal enhancement for a wide range of biomolecules at the trace level. This makes PIERS a powerful technique with very appealing and promising applications in various branches of analytical science. In this review, the enhancement mechanisms of PIERS are analyzed in comparison with SERS. Afterward, the parameters influencing the enhancement of PIERS, including the substrate, light irradiation, and relaxation are discussed in detail. Finally, some perspectives on further developments of PIERS are exemplified. The PIERS technique will continue to evolve and grow with new developments and its successful application in bioanalysis and life sciences.
光处理作为一种推动结构转变、光谱和电磁改进以及纳米材料功能性能的研究热点，处于领先地位。光照射可以在贵金属纳米粒子中激发出表面等离激元，产生电子-空穴对，并在半导体衬底中产生电荷转移，这导致它在生命科学、环境保护和生物分析等领域的表面增强拉曼光谱（SERS）中得到了广泛应用。光诱导增强拉曼光谱（PIERS）是在传统 SERS 基础上发展起来的一项新技术，由于其在连续操作、高效电荷分离和富集以及对痕量水平的各种生物分子的广泛信号增强方面具有无与伦比的优势，已被证明是解决几个关键挑战的有效方法。这使得 PIERS 成为一种强大的技术，在分析科学的各个分支中具有非常有吸引力和广阔的应用前景。在这篇综述中，通过与 SERS 进行比较，分析了 PIERS 的增强机制。随后，详细讨论了影响 PIERS 增强的参数，包括基底、光照射和弛豫。最后，举例说明了对 PIERS 进一步发展的一些展望。PIERS 技术将随着新的发展和在生物分析和生命科学中的成功应用而不断发展和壮大。
