Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan, Shandong Province, PR China; Engineering Research Center of Zebrafish Models for Human Diseases and Drug Screening of Shandong Province, Jinan, Shandong Province, PR China.
Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan, Shandong Province, PR China; Engineering Research Center of Zebrafish Models for Human Diseases and Drug Screening of Shandong Province, Jinan, Shandong Province, PR China.
Environ Res. 2021 Jul;198:111281. doi: 10.1016/j.envres.2021.111281. Epub 2021 May 5.
Due to intense industrialization and urbanization, air pollution has become a serious global concern as a hazard to human health. Epidemiological studies found that exposure to atmospheric particulate matter (PM) causes severe health problems in human and significant damage to the physiological systems. In recent days, PM exposure could be related as a carrier for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus transmission and Coronavirus disease 2019 (COVID-19) infection. Hence, it is important to understand the adverse effects of PM in human health. This review aims to provide insights on the detrimental effects of PM in various human health problems including respiratory, circulatory, nervous, and immune system along with their possible toxicity mechanisms. Overall, this review highlights the potential relationship of PM with several life-limiting human diseases and their significance for better management strategies.
由于工业化和城市化的加剧，空气污染已成为危害人类健康的严重全球性问题。流行病学研究发现，大气颗粒物（PM）的暴露会对人类造成严重的健康问题，并对生理系统造成重大损害。最近，PM 的暴露可能与严重急性呼吸系统综合征冠状病毒 2（SARS-CoV-2）病毒的传播和 2019 年冠状病毒病（COVID-19）感染有关。因此，了解 PM 对人类健康的不良影响很重要。本综述旨在提供有关 PM 对各种人类健康问题（包括呼吸系统、循环系统、神经系统和免疫系统）的有害影响的见解，并探讨其可能的毒性机制。总的来说，本综述强调了 PM 与几种危及生命的人类疾病的潜在关系，以及它们对于更好的管理策略的重要性。
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