Departamento de Farmácia, Universidade Federal de Sergipe, Avenida Marechal Rondon, s/n, Cidade Universitária, CEP 49100-000 São Cristóvão, SE, Brazil.
Nutrition and Dietetics School, University of Atlántico, Atlántico, Colombia.
Food Chem. 2021 Oct 15;359:129975. doi: 10.1016/j.foodchem.2021.129975. Epub 2021 Apr 28.
Formononetin (FORM) is an isoflavone from the group of phytoestrogens that exhibits a broad spectrum of physiological effects beneficial to health through dependent and independent mechanisms of estrogen. This article aimed to present FORM main functions and future prospects for applications in different areas. Scientific publications and patents dated between 1998 and 2019 were analyzed. FORM has potential as an active compound of interest to product development for the industries of food, medicine, and cosmetics, among others. Moreover, in the medical area, this active compound has shown potential in the prevention and treatment of several diseases, including chronic ones, such as cancer, obesity, and neurodegenerative diseases.
芒柄花素（FORM）是植物雌激素类异黄酮的一种，通过雌激素依赖和非依赖机制，表现出广泛的有益于健康的生理作用。本文旨在介绍芒柄花素的主要功能和未来在不同领域应用的前景。分析了 1998 年至 2019 年期间的科学出版物和专利。芒柄花素有可能成为食品、医药和化妆品等行业产品开发的活性化合物。此外，在医学领域，这种活性化合物在预防和治疗包括癌症、肥胖和神经退行性疾病等慢性疾病方面显示出了潜力。
