Suppr超能文献

旋毛虫病:埃塞俄比亚最被忽视的热带病。

Strongyloidiasis: the most neglected tropical disease in Ethiopia.

机构信息

School of Medical Laboratory Sciences, Institute of Health, Jimma University, Jimma, Ethiopia.

出版信息

Infect Dis Poverty. 2021 May 7;10(1):65. doi: 10.1186/s40249-021-00851-2.

Abstract

BACKGROUND

Strongyloidiasis is the most neglected of the neglected tropical diseases (NTDs). The aim of this commentary is to describe the possible reasons why strongyloidiasis is so overlooked in Ethiopia, and shed light on better ways of control and elimination of the disease.

MAIN BODY

This commentary highlights three points why strongyloidiasis is the most neglected of the NTDs in Ethiopia. Firstly, lack of clear category within the NTDs resulted in omission of the disease from reports, intervention programs, and preventive chemotherapy guidelines. Secondly, magnitude of the disease is underestimated due to paucity of studies and low sensitivity of diagnostic methods coupled with asymptomatic nature of most of the infections. Finally, ivermectin (the drug of choice for treatment of strongyloidiasis) is not in use for control of the other soil-transmitted helminthiasis, nor is there ivermectin mass drug administration for control of strongyloidiasis. This might have created gap in control and elimination of the disease in Ethiopia and possibly elsewhere.

CONCLUSION

Strongyloidiasis appears to be the most neglected of the NTDs mainly due to nature of the infection, low sensitivity of the routine diagnostic tools and it's exclusion from strategic plans and intervention programs. Moreover, studies on strongyloidiasis should use sensitive diagnostic tools. Strongyloidiasis control and elimination programs should be based on reliable evidence of epidemiology of the disease in Ethiopia.

摘要

背景

类圆线虫病是被忽视的热带病(NTDs)中最被忽视的一种。本文的目的是描述类圆线虫病在埃塞俄比亚被如此忽视的可能原因,并探讨更好的控制和消除该疾病的方法。

正文

本文强调了类圆线虫病为何是埃塞俄比亚 NTDs 中最被忽视的三个原因。首先,由于缺乏明确的 NTDs 类别,导致该疾病在报告、干预计划和预防性化疗指南中被遗漏。其次,由于研究匮乏、诊断方法敏感性低以及大多数感染呈无症状特征,导致疾病的严重程度被低估。最后,用于治疗类圆线虫病的伊维菌素(首选药物)并未用于控制其他土壤传播性蠕虫病,也未进行伊维菌素大规模药物治疗以控制类圆线虫病。这可能在埃塞俄比亚及其他地方造成该疾病控制和消除的空白。

结论

类圆线虫病似乎是最被忽视的 NTDs 之一,主要是由于感染的性质、常规诊断工具的低敏感性以及其被排除在战略计划和干预计划之外。此外,类圆线虫病的研究应使用敏感的诊断工具。类圆线虫病的控制和消除计划应基于该疾病在埃塞俄比亚的可靠流行病学证据。

相似文献

引用本文的文献

1
Neglected Tropical Diseases: A Comprehensive Review.被忽视的热带病:全面综述
Cureus. 2024 Feb 9;16(2):e53933. doi: 10.7759/cureus.53933. eCollection 2024 Feb.

本文引用的文献

1
The Global Prevalence of Infection.感染的全球流行情况。
Pathogens. 2020 Jun 13;9(6):468. doi: 10.3390/pathogens9060468.
5
Novel approaches to the diagnosis of Strongyloides stercoralis infection.新型诊断方法用于粪类圆线虫感染的诊断。
Clin Microbiol Infect. 2015 Jun;21(6):543-52. doi: 10.1016/j.cmi.2015.04.001. Epub 2015 Apr 14.
6
Strongyloides stercoralis: Global Distribution and Risk Factors.粪类圆线虫:全球分布和危险因素。
PLoS Negl Trop Dis. 2013 Jul 11;7(7):e2288. doi: 10.1371/journal.pntd.0002288. Print 2013.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验