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不同前凸椎间融合器角度下腰椎侧方椎间融合术后节段性及腰椎前凸的变化

Changes in Segmental and Lumbar Lordosis After Lateral Lumbar Interbody Fusion With Different Lordotic Cage Angulations.

作者信息

Bakare Adewale A, Fessler David R, Wewel Joshua T, Fontes Ricardo B V, Fessler Richard G, O'Toole John E

机构信息

Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois.

Piedmont Healthcare, Atlanta Brain and Spine, Atlanta, Georgia.

出版信息

Int J Spine Surg. 2021 Jun;15(3):440-448. doi: 10.14444/8066. Epub 2021 May 7.

Abstract

BACKGROUND

Lateral lumbar interbody fusion (LLIF) affords a wide operative corridor to allow for a large interbody cage implantation for segmental reconstruction. There is a paucity of data describing segmental lordosis (SL) achieved with lordotic implants of varying angles. Here we compare changes in SL and lumbar lordosis (LL) after implantation of 6°, 10°, and 12° cages.

METHODS

We retrospectively reviewed LLIF cases over a 5.5-year period. We derived SL and LL using the standard cobb angle measurement from a standing lateral radiograph. We analyzed mean changes in SL and LL over time using the linear mixed effect model to estimate these longitudinal changes.

RESULTS

The most frequently treated level was L3-4, followed by L4-5. Significant increases in mean SL were found at each follow-up time point for all the cohorts. In an intercohort comparison, the mean changes in SL at immediate postoperative and last follow-up were significantly greater in the 10° cohort than 6° ([7.4° versus 3.1°, .004], [6.1° versus 2.3°, = .025] respectively). The 12° cohort had higher mean change in SL at last follow-up than the 6° cohort (5.9° versus 2.3°, = .022). There was no difference in mean change in SL between the 10° and 12° cohorts. No difference in overall mean LL over time was found. In terms of mean change in LL, no difference was observed except at immediate and 6-month postoperative in the 10° cohort ([9.6°, = .001], [8.5, = .003] respectively). By comparing mean change in LL, no difference existed except between the 10° and 6° immediately after surgery (9.6° versus 0.2°, = .006).

CONCLUSIONS

LLIF cages significantly improve SL at the index level. However, this increase in SL is greater for 10° and 12° cages than the standard 6° cage. Use of 10° cages also resulted in overall improved LL than 6° cages.

LEVEL OF EVIDENCE

CLINICAL RELEVANCE

Lateral lumbar interbody fusion.

摘要

背景

腰椎外侧椎间融合术(LLIF)提供了广阔的手术通道,以便植入大型椎间融合器进行节段性重建。关于不同角度的前凸椎间融合器实现的节段性前凸(SL)的数据较少。在此,我们比较了植入6°、10°和12°椎间融合器后SL和腰椎前凸(LL)的变化。

方法

我们回顾性分析了5.5年期间的LLIF病例。我们使用站立位侧位X线片上的标准 Cobb角测量法得出SL和LL。我们使用线性混合效应模型分析SL和LL随时间的平均变化,以估计这些纵向变化。

结果

最常治疗的节段是L3-4,其次是L4-5。在所有队列的每个随访时间点,平均SL均有显著增加。在队列间比较中,10°队列术后即刻和末次随访时SL的平均变化显著大于6°队列(分别为[7.4°对3.1°,P =.004],[6.1°对2.3°,P =.025])。12°队列末次随访时SL的平均变化高于6°队列(5.9°对2.3°,P =.022)。10°和12°队列之间SL的平均变化无差异。未发现LL随时间的总体平均变化有差异。就LL的平均变化而言,除10°队列术后即刻和6个月时(分别为[9.6°,P =.001],[8.5°,P =.003])外,未观察到差异。通过比较LL的平均变化,除手术刚结束时10°和6°之间(9.6°对0.2°,P =.006)外,无差异。

结论

LLIF椎间融合器显著改善了手术节段的SL。然而,10°和12°椎间融合器的SL增加幅度大于标准的6°椎间融合器。使用10°椎间融合器也比6°椎间融合器总体上改善了LL。

证据水平

3级。

临床相关性

腰椎外侧椎间融合术。

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