Butt W, Barker G, Walker C, Gillis J, Kilham H, Stevens M
Intensive Care Unit, Royal Children's Hospital, Victoria, Australia.
Crit Care Med. 1988 Aug;16(8):761-4. doi: 10.1097/00003246-198808000-00005.
Sixty-four (48%) of 133 children with hematologic malignancy who were admitted to three pediatric ICUs died. Children who required management because of airway obstruction or after general anesthesia had the best outlook (mortality rate of 7% or less); those children who required major circulatory support or mechanical ventilation for hypoxemia did poorly (mortality rate of 84% or greater). Certain conditions in children with hematologic malignancy that require intensive care are associated with a mortality rate of approximately 75%. These include the following: suspected sepsis, interstitial pneumonitis, encephalopathy due to sepsis or hemorrhage. In children with these life-threatening conditions, therapy must be improved because at this stage, the patients do not benefit from admission to the ICU.
133名入住三家儿科重症监护病房（ICU）的血液系统恶性肿瘤患儿中，64名（48%）死亡。因气道梗阻或全身麻醉后需要治疗的患儿预后最佳（死亡率为7%或更低）；那些因低氧血症需要主要循环支持或机械通气的患儿预后较差（死亡率为84%或更高）。血液系统恶性肿瘤患儿中某些需要重症监护的情况，死亡率约为75%。这些情况包括：疑似脓毒症、间质性肺炎、脓毒症或出血所致脑病。对于患有这些危及生命疾病的患儿，必须改进治疗方法，因为在此阶段，患者入住ICU并无益处。
