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分析肺癌放疗患者 SPECT 通气与 SPECT 灌注的空间差异。

Characterizing spatial differences between SPECT-ventilation and SPECT-perfusion in patients with lung cancer undergoing radiotherapy.

机构信息

Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO, United States.

Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO, United States, United States(1); Department of Radiation Oncology, Mayo Clinic, Rochester, MN, United States(2).

出版信息

Radiother Oncol. 2021 Jul;160:120-124. doi: 10.1016/j.radonc.2021.04.022. Epub 2021 May 6.

DOI:10.1016/j.radonc.2021.04.022
PMID:33964328
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8489737/
Abstract

This study investigates agreement between ventilation and perfusion for lung cancer patients undergoing radiotherapy. Ventilation-perfusion scans of nineteen patients with stage III lung cancer from a prospective protocol were compared using voxel-wise Spearman correlation-coefficients. The presented results show in about 25% of patients, ventilation and perfusion exhibit lower agreement.

摘要

本研究调查了接受放疗的肺癌患者通气与灌注的一致性。通过体素-wiseSpearman 相关系数比较了前瞻性方案中 19 例 III 期肺癌患者的通气-灌注扫描。结果表明，约 25%的患者通气和灌注的一致性较低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73df/8489737/4f033dc44a0a/nihms-1700997-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73df/8489737/7b6c3b39d589/nihms-1700997-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73df/8489737/4f033dc44a0a/nihms-1700997-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73df/8489737/7b6c3b39d589/nihms-1700997-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/73df/8489737/4f033dc44a0a/nihms-1700997-f0002.jpg

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本文引用的文献

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Adv Radiat Oncol. 2020 Mar 20;5(3):459-465. doi: 10.1016/j.adro.2020.03.002. eCollection 2020 May-Jun.
2
The VAMPIRE challenge: A multi-institutional validation study of CT ventilation imaging.VAMPIRE 挑战赛：CT 通气成像的多机构验证研究。
Med Phys. 2019 Mar;46(3):1198-1217. doi: 10.1002/mp.13346. Epub 2019 Feb 1.
3
Interim Analysis of a Two-Institution, Prospective Clinical Trial of 4DCT-Ventilation-based Functional Avoidance Radiation Therapy.
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Int J Radiat Oncol Biol Phys. 2024 Oct 1;120(2):370-408. doi: 10.1016/j.ijrobp.2024.04.001. Epub 2024 Apr 15.
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4DCT ventilation function image-based functional lung protection for esophageal cancer radiotherapy.基于4DCT通气功能图像的食管癌放疗肺功能保护
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