Choudhury S R, Williams T H
Acta Anat (Basel). 1978;100(3):273-81. doi: 10.1159/000144909.
The effects of septal cannulation on the displacement of basal ganglia form the basis of the present communication. In experimental rats, in which a cannula is chronically implanted for 30 days between the medial and lateral septal nuclei by stereotaxic procedures, considerable shift of the basal ganglion is always observed on the operated side. The displacement takes place along the long axis of the ganglion either rostrally or caudally. Besides gross asymmetry in their relative sizes, no histological differences are observed between the ganglia of the two sides. Control animals, in which the cannula is withdrawn immediately after the septal lesion, manifest similar, but less pronounced movements of the basal ganglia. The probable underlying mechanisms for such intracerebral shifts are discussed and the role of indirect mechanical forces is outlined. The extraordinary degree of plasticity of the subcortical nuclear masses in terms of mobility is also emphasized.
中隔插管对基底神经节移位的影响构成了本报告的基础。在实验大鼠中，通过立体定位手术将插管长期植入内侧和外侧中隔核之间30天，总是观察到手术侧基底神经节有相当大的移位。移位沿着神经节的长轴向前或向后发生。除了两侧神经节相对大小存在明显不对称外，未观察到组织学差异。在中隔损伤后立即拔出插管的对照动物，基底神经节也表现出类似但不太明显的运动。讨论了这种脑内移位可能的潜在机制，并概述了间接机械力的作用。还强调了皮质下核团在移动性方面具有的非凡可塑性程度。
