肿瘤更偏好宿主而非膳食营养：“饥饿疗法”的秘密被揭开了。
The CAT-SIR is out of the bag: tumors prefer host rather than dietary nutrients.
机构信息
Koch Institute for Integrative Cancer Research and the Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Dana-Farber Cancer Institute, Boston, MA, 02215, USA.
出版信息
BMC Biol. 2021 May 10;19(1):92. doi: 10.1186/s12915-021-01027-y.
The extent to which tumors acquire nutrients from dietary sources as opposed to from the breakdown of host tissues is not known. In this issue of BMC Biology, Holland et al. report an approach where food sources with different isotope labeled carbon ratios can be used to answer this question, and find that tumors arising in Drosophila melanogaster procure most of their nutrients from the host.
肿瘤从饮食来源获取营养的程度与从宿主组织分解获取营养的程度相比如何尚不清楚。在本期 BMC 生物学杂志中，Holland 等人报告了一种可以使用具有不同同位素标记碳比的食物来源来回答这个问题的方法，并发现果蝇中产生的肿瘤主要从宿主获取营养。
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