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上颌骨透明细胞牙源性癌:一例罕见病例报告。

Clear cell odontogenic carcinoma in maxilla: A rare case report.

作者信息

Patankar Swapna Amod, Raut Pratik, Patankar Amod Pramod, Kshirsagar Rajesh Ashok

机构信息

Department of Oral and Maxillofacial Pathology and Oral Microbiology, Bharati Vidyapeeth Dental College and Hospital, Pune, Maharashtra, India.

Department of Consultant Maxillofacial Surgeon in Pune, Pune, Maharashtra, India.

出版信息

J Oral Maxillofac Pathol. 2020 Sep-Dec;24(3):590. doi: 10.4103/jomfp.JOMFP_298_20. Epub 2021 Jan 9.

DOI:10.4103/jomfp.JOMFP_298_20
PMID:33967522
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8083418/
Abstract

A rare and aggressive form of tumor with a female predilection and more seen with mandible is the clear cell odontogenic carcinoma (CCOC). The World Health Organization categorized it as a malignant neoplasm in 2005. This type of tumor is characterized by local recurrences as well as distant metastasis apart from being highly aggressive in nature. Due to the presence of clear cells, it is a diagnostic challenge to the pathologist. Only about 84 cases of maxillary variant have been reported in the literature. Here, we present a case report of a 31-year-old male with CCOC in the maxilla from the pathological and diagnostic point of view.

摘要

透明细胞牙源性癌(CCOC)是一种罕见且侵袭性强的肿瘤,女性多见,在下颌骨更为常见。2005年世界卫生组织将其归类为恶性肿瘤。这种肿瘤除了本质上具有高度侵袭性外,还具有局部复发和远处转移的特点。由于存在透明细胞,对病理学家来说是一个诊断挑战。文献中仅报道了约84例上颌骨变异型病例。在此,我们从病理和诊断角度报告一例31岁上颌骨透明细胞牙源性癌男性病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc1c/8083418/e843b95dd104/JOMFP-24-590b-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc1c/8083418/21efc01f7a06/JOMFP-24-590b-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc1c/8083418/95a50a00001f/JOMFP-24-590b-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc1c/8083418/05bf034eeb9f/JOMFP-24-590b-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc1c/8083418/e843b95dd104/JOMFP-24-590b-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc1c/8083418/21efc01f7a06/JOMFP-24-590b-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc1c/8083418/95a50a00001f/JOMFP-24-590b-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc1c/8083418/05bf034eeb9f/JOMFP-24-590b-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc1c/8083418/e843b95dd104/JOMFP-24-590b-g004.jpg

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本文引用的文献

1
Clear cell odontogenic carcinoma of mandible: An unclarified entity.下颌骨透明细胞牙源性癌:一种尚不明确的实体。
J Oral Maxillofac Pathol. 2018 Sep-Dec;22(3):392-395. doi: 10.4103/jomfp.JOMFP_117_18.
2
Clear cell odontogenic carcinoma: A rare case report with emphasis on differential diagnosis.透明细胞牙源性癌:1例罕见病例报告并着重于鉴别诊断
J Cancer Res Ther. 2017 Apr-Jun;13(2):374-377. doi: 10.4103/0973-1482.187381.
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Clear cell odontogenic carcinoma of the mandible and temporomandibuar joint with cervical lymph nodal metastasis.
下颌骨及颞下颌关节透明细胞牙源性癌伴颈部淋巴结转移。
Natl J Maxillofac Surg. 2014 Jul-Dec;5(2):221-3. doi: 10.4103/0975-5950.154842.
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Histomorphological array in odontogenic keratocyst.牙源性角化囊肿的组织形态学表现
J Oral Maxillofac Pathol. 2013 Jan;17(1):143-5. doi: 10.4103/0973-029X.110724.
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Clear cell odontogenic carcinoma of maxilla: A case report and mini review.上颌骨透明细胞牙源性癌:一例报告及简要综述
J Oral Maxillofac Pathol. 2013 Jan;17(1):89-94. doi: 10.4103/0973-029X.110681.
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An asymptomatic radiolucent lesion of the maxilla. Clear cell odontogenic carcinoma.上颌骨的无症状透射性病变。透明细胞牙源性癌。
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Clear cell odontogenic carcinoma: evaluation of reported cases.透明细胞牙源性癌:已报道病例分析
J Oral Maxillofac Surg. 2003 May;61(5):580-6. doi: 10.1053/joms.2003.50114.
8
Clear cell odontogenic carcinoma: a clinicopathologic and immunocytochemical study of 5 cases.透明细胞牙源性癌:5例临床病理及免疫细胞化学研究
Arch Pathol Lab Med. 2001 Dec;125(12):1566-71. doi: 10.5858/2001-125-1566-CCOC.
9
Radiographic manifestation of clear cell odontogenic tumor.透明细胞牙源性肿瘤的影像学表现。
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000 Feb;89(2):250-4. doi: 10.1067/moe.2000.101796.
10
Clear cell neoplasms in salivary glands: clearly a diagnostic challenge.唾液腺中的透明细胞肿瘤:显然是一项诊断挑战。
Ann Diagn Pathol. 1998 Feb;2(1):61-78. doi: 10.1016/s1092-9134(98)80035-x.