Kohler B, Köhler G, Riemann J F
Medizinischen Klinik C, Klinikum der Stadt Ludwigshafen am Rhein, Ludwigshafen, Federal Republic of Germany.
Gastroenterology. 1988 Sep;95(3):828-30. doi: 10.1016/s0016-5085(88)80035-0.
In a 50-yr-old male patient, a spontaneously perforating peptic ulcer located in a patch of heterotopic gastric mucosa in the upper part of the esophagus led to the development of an esophagotracheal fistula. The histologic workup revealed, in addition to ulcer necroses and granulation tissue, glands of the fundic type, with chief and parietal cells. On the basis of histologic results, the fistula was successfully occluded with the aid of a fibrin adhesive applied endoscopically. After the second session, the patient immediately became free of symptoms. Under medical treatment with an H2-receptor blocker, the patient has been completely symptom-free for 1 yr.
在一名50岁男性患者中，位于食管上段一片异位胃黏膜处的自发性穿孔性消化性溃疡导致了食管气管瘘的形成。组织学检查除发现溃疡坏死和肉芽组织外，还发现了具有主细胞和壁细胞的胃底型腺体。根据组织学检查结果，在内镜下应用纤维蛋白黏合剂成功封闭了瘘管。第二次治疗后，患者症状立即消失。在使用H2受体阻滞剂进行药物治疗后，患者已完全无症状达1年。
