Kohler B, Köhler G, Riemann J F
Dtsch Med Wochenschr. 1987 Jul 10;112(28-29):1130-3. doi: 10.1055/s-2008-1068207.
A tracheo-esophageal fistula occurred spontaneously in a 50-year-old man. At endoscopy it was found to be due to a perforated ulcer localized in heterotopic gastric mucosa in the cervical esophagus. Histological examination revealed ulcer necrosis and granulation tissue, as well as glands of the stomach type with chief and other cells. Malignant or specific genesis was excluded. Based on the histological finding, the attempt was successfully made of closing the fistula with fibrin glue in two sittings. All symptoms ceased immediately after the second sitting. Later radiological and endoscopic examinations no longer demonstrated either the fistula opening nor a fistulous tract.
一名50岁男性自发出现气管食管瘘。内镜检查发现其病因是位于颈段食管异位胃黏膜处的溃疡穿孔。组织学检查显示溃疡坏死、肉芽组织以及胃型腺体，包括主细胞和其他细胞。排除了恶性或特异性病因。基于组织学检查结果，分两次成功尝试用纤维蛋白胶封闭瘘管。第二次治疗后所有症状立即消失。后来的放射学和内镜检查均未再发现瘘口或瘘管。
