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一名儿科患者出现长时间癫痫发作,随后发生严重高磷血症和低钙血症。

Prolonged Seizure Activity Followed by Severe Hyperphosphatemia and Hypocalcemia in a Pediatric Patient.

作者信息

Coriell Megan B, Van Hersh Andrew T, Shah Siddharth

机构信息

Pediatric Endocrinology, University of Louisville School of Medicine, Louisville, USA.

Pediatrics, University of Louisville School of Medicine, Louisville, USA.

出版信息

Cureus. 2021 Apr 7;13(4):e14338. doi: 10.7759/cureus.14338.

Abstract

Seizures secondary to hypocalcemia have been well documented and studied. There are various causes of hypocalcemia described in the literature, but a prolonged seizure episode leading to cell lysis, severe hyperphosphatemia, and hypocalcemia is rarely reported. We present the case of a 3-year-old male with severe hyperphosphatemia and hypocalcemia secondary to the likely presence of cell lysis from prolonged seizure activity. Our case illustrates the importance of a thorough evaluation of the possible differentials of hypocalcemia and hyperphosphatemia in a challenging presentation.

摘要

低钙血症继发的癫痫发作已有充分的文献记载和研究。文献中描述了低钙血症的各种病因,但因长时间癫痫发作导致细胞溶解、严重高磷血症和低钙血症的情况鲜有报道。我们报告了一例3岁男性患儿,因长时间癫痫活动可能导致细胞溶解继发严重高磷血症和低钙血症。我们的病例说明了在具有挑战性的病例中对低钙血症和高磷血症可能的鉴别诊断进行全面评估的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d91c/8103793/029ddc9de749/cureus-0013-00000014338-i01.jpg

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