Anuradha Chelliah, Selvarajan R, Jebasingh T, Sankara Naynar P
ICAR-National Research Centre for Banana, Thogamalai Road, Thayanur Post, Tiruchirappalli, Tamil Nadu India.
Department of Plant Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai, Tamil Nadu India.
Virusdisease. 2021 Mar;32(1):123-130. doi: 10.1007/s13337-021-00672-9. Epub 2021 Apr 5.
(BBrMV), belongs to the genus and it is an important viral pathogen of bananas and plantains. The eukaryotic translation initiation factor, eIF4E, and its isoform play key roles during the virus infection in plants, particularly . The present study was undertaken to determine the role of BBrMV-viral protein genome-linked (VPg) in virus infectivity by analyzing the interaction with the eukaryotic translation initiation factor eIF4E through yeast two-hybrid system. The results suggest that plantain cv. Nendran eIF4E plays an essential role in the initiation of the translation of capped mRNAs and its association with VPg would point to a role of the viral protein in the translation of the virus and may potentially contribute to BBrMV resistance.
香蕉束顶病毒（BBrMV）属于该属，是香蕉和大蕉的一种重要病毒病原体。真核翻译起始因子eIF4E及其同工型在植物病毒感染过程中发挥关键作用，尤其是在……期间。本研究旨在通过酵母双杂交系统分析香蕉束顶病毒病毒蛋白基因组连接蛋白（VPg）与真核翻译起始因子eIF4E的相互作用，以确定其在病毒感染性中的作用。结果表明，大蕉品种Nendran的eIF4E在加帽mRNA翻译起始中起重要作用，其与VPg的关联表明该病毒蛋白在病毒翻译中起作用，可能有助于香蕉束顶病毒抗性。
