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小儿纤维支气管镜检查:单中心报告。

Pediatric flexible bronchoscopy: A single-center report.

机构信息

Department of Women's and Children's Health, University of Padova, Padua, Italy.

出版信息

Pediatr Pulmonol. 2021 Aug;56(8):2634-2641. doi: 10.1002/ppul.25458. Epub 2021 May 18.

Abstract

INTRODUCTION

Pediatric flexible laryngotracheal bronchoscopy (FB) is an integral part of diagnostics and treatment at tertiary pediatric respiratory centers.

AIM

FBs performed between 2013 and 2018 at our Pediatric Allergy and Respiratory Medicine Unit of the Department of Women's and Children's Health at Padua University were examined in terms of the indications, findings, and adverse events.

MATERIALS AND METHODS

The electronic medical records of pediatric patients who underwent FB at least once between 1 January 2013 and 31 December 2018 were considered. Patients' clinical data, indications for FB, anatomical findings, information derived from bronchoalveolar lavage (BAL) and bronchial brushing, and possible adverse events were analyzed.

RESULTS

There were 447 pediatric FBs performed in 428 patients (aged from 1 month to 18 years) for diagnostic purposes (92.4%), to clear secretions (3.6%), or to monitor a known condition (4.0%). The main indications were recurrent lower respiratory tract infections (LRTI, 32.2%) and chronic wet cough (9.4%). Lower airway malacia was the most common abnormal finding in these two groups (36.1% and 28.6%, respectively). BAL bacterial culture was positive in 55 children (39.6%) with recurrent LRTI and in 25 (59.5%) with chronic wet cough, being Haemophilus influenzae, Streptococcus pneumoniae, and Moraxella catarrhalis the microorganisms most commonly isolated. FB proved a safe procedure and was well tolerated.

CONCLUSIONS

Pediatric FB is an essential tool at our tertiary pediatric respiratory center. It helps establish the anatomical conditions underlying several chronic respiratory conditions and any correlated microbiological findings, with a significant impact on further patient management.

摘要

简介

儿科软性喉气管支气管镜检查(FB)是三级儿科呼吸中心诊断和治疗的重要组成部分。

目的

检查 2013 年至 2018 年期间在我们的帕多瓦大学妇女和儿童健康系儿科过敏和呼吸医学科进行的 FB,检查其适应证、结果和不良事件。

材料和方法

考虑至少在 2013 年 1 月 1 日至 2018 年 12 月 31 日期间接受过 FB 的儿科患者的电子病历。分析患者的临床数据、FB 的适应证、解剖学发现、支气管肺泡灌洗(BAL)和支气管刷检获得的信息以及可能的不良事件。

结果

在 428 例患者(年龄 1 个月至 18 岁)中进行了 447 次儿科 FB,其中诊断目的(92.4%)、清除分泌物(3.6%)或监测已知疾病(4.0%)。主要适应证为复发性下呼吸道感染(LRTI,32.2%)和慢性湿咳(9.4%)。下气道软化是这两组中最常见的异常发现(分别为 36.1%和 28.6%)。复发性 LRTI 患儿中 55 例(39.6%)BAL 细菌培养阳性,慢性湿咳患儿中 25 例(59.5%)BAL 细菌培养阳性,最常分离出的微生物为流感嗜血杆菌、肺炎链球菌和卡他莫拉菌。FB 是一种安全的程序,耐受性良好。

结论

儿科 FB 是我们三级儿科呼吸中心的重要工具。它有助于确定几种慢性呼吸系统疾病的解剖条件和任何相关的微生物学发现,对进一步的患者管理有重要影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4f5/8360175/33aa9f028a04/PPUL-56-2634-g001.jpg

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