Maj Institute of Pharmacology, Polish Academy of Sciences, Kraków, Poland.
Nat Prod Res. 2022 Oct;36(20):5337-5341. doi: 10.1080/14786419.2021.1920583. Epub 2021 May 8.
This is the first report concerning the natural products of the hitherto unstudied (L.) Gren. & Godr., a member of the tribe Cichorieae (Asteraceae). From aerial parts and roots of this plant, five sesquiterpene lactones and one coumarin were isolated. The compounds were identified as sonchuside A, 11β,13-dihydrolactucin-8--acetate, 11β,13-dihydrolactucin, cichorioside B, 11β,13-dihydrolactucin-8--acetate-15--β-glucopyranoside and coumarin - cichoriin. Their structures were established by H NMR. Moreover, HPLC/PAD analysis of a hydroalcoholic extract from the aerial parts of the plant revealed the presence of caffeic acid derivatives, coumarins and flavonoids commonly found in lettuces.[Formula: see text].
这是有关迄今尚未研究过的(L.)Gren. & Godr.(菊科菊苣族成员)植物天然产物的首份报告。从该植物的地上部分和根部分离出五种倍半萜内酯和一种香豆素。这些化合物被鉴定为 sonchuside A、11β,13-二氢乳清酸-8-O-乙酸酯、11β,13-二氢乳清酸、cichorioside B、11β,13-二氢乳清酸-8-O-乙酸酯-15-β-吡喃葡萄糖苷和香豆素-菊苣苷。它们的结构通过 1H NMR 确定。此外,对植物地上部分的水醇提取物进行 HPLC/PAD 分析显示,存在咖啡酸衍生物、香豆素和在生菜中常见的类黄酮。