用于在活细胞膜上成像和跟踪受体的不闪烁碳点。
Nonblinking carbon dots for imaging and tracking receptors on a live cell membrane.
机构信息
State Key Laboratory of Heavy Oil Processing and Centre for Bioengineering and Biotechnology, China University of Petroleum (East China), Qingdao, 266580, China.
出版信息
Chem Commun (Camb). 2021 Jun 7;57(45):5554-5557. doi: 10.1039/d1cc01120k. Epub 2021 May 10.
PMID:33969837
Abstract
Blinking occurs with nearly all fluorophores including organic dyes, fluorescent proteins, semiconductor quantum dots and carbon dots (CDs). We developed non-blinking and photoresistant fluorescent CDs by introducing multiple aromatic domains onto a single carbon dot and demonstrated their great potential for imaging and tracking of receptors on a live cell membrane.
摘要
几乎所有的荧光团都会发生闪烁现象，包括有机染料、荧光蛋白、半导体量子点和碳点（CDs）。我们通过在单个碳点上引入多个芳香结构域来开发出不闪烁和抗光漂白的荧光 CDs，并展示了它们在活细胞膜上对受体进行成像和跟踪的巨大潜力。
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