Friedlaender M H, Cavanagh H D, Sullivan W R, Gallagher M J, Dickersin G R
Am J Ophthalmol. 1977 Dec;84(6):781-7. doi: 10.1016/0002-9394(77)90496-2.
A 55-year-old woman developed a skin rash and lipid deposition centrally in previously normal corneas. Despite a family history of coronary artery disease, no serum lipid abnormality was detected. Lipid droplets and granules were deposited throughout the corneal epithelium and stroma. Histochemical stains were positive only for phosopholipid and galactolipid. After a keratoplasty, deposition of similar lipid material recurred in the graft. An inflammatory process and increased corneosceleral limbal vascular permeability may have accounted for the unusual corneal findings in this patient.
一名55岁女性在原本正常的角膜中央出现皮疹和脂质沉积。尽管有冠状动脉疾病家族史，但未检测到血清脂质异常。脂质小滴和颗粒沉积于整个角膜上皮和基质。组织化学染色仅对磷脂和半乳糖脂呈阳性。角膜移植术后，移植片中再次出现类似脂质物质的沉积。炎症过程和角膜巩膜缘血管通透性增加可能是该患者角膜出现异常表现的原因。
