Dermatology Unit, ASST Lecco, Alessandro Manzoni Hospital, Lecco, Italy.
UOC Dermatology, Department of Pathophysiology and Transplantation, University of Milan, Foundation IRCCS, Cà Granda Maggiore Policlinico Hospital, Milan, Italy.
Clin Dermatol. 2021 Jan-Feb;39(1):12-22. doi: 10.1016/j.clindermatol.2020.12.008. Epub 2020 Dec 17.
A wide range of cutaneous signs are attributed to COVID-19 infection. This retrospective study assesses the presence and impact of dermatologic manifestations related to the spread of COVID-19 in Lombardy, the geographic district with the first outbreak in Italy. A cohort of 345 patients with laboratory confirmed COVID-19 was collected from February 1, 2020 to May 31, 2020. Cutaneous signs and dermatologic diagnoses were recorded on admission, and during the course of the disease. Of the 345 patients included in the study, 52 (15%) had new-onset dermatologic conditions related to COVID-19. We observed seven major cutaneous clinical patterns, merged under 3 main groups: Exanthems, vascular lesions, and other cutaneous manifestations. Each subset was detailed with prevalence, age, duration, prognosis, and histology. Cutaneous findings can lead to suspect COVID-19 infection and identify potentially contagious cases with indolent course.
许多皮肤表现与 COVID-19 感染有关。本回顾性研究评估了 COVID-19 在意大利首次爆发地区伦巴第大区传播期间相关皮肤表现的出现和影响。我们收集了 2020 年 2 月 1 日至 2020 年 5 月 31 日期间实验室确诊的 COVID-19 患者 345 例。在入院时和疾病过程中记录皮肤表现和皮肤病诊断。在纳入研究的 345 例患者中,52 例(15%)有新发与 COVID-19 相关的皮肤病。我们观察到七种主要的皮肤临床模式,合并为 3 大组:出疹、血管病变和其他皮肤表现。每个亚组都详细描述了患病率、年龄、病程、预后和组织学。皮肤表现可提示 COVID-19 感染,并发现潜在具有惰性病程的传染性病例。