Oral and Maxillofacial Surgery, Worcestershire Acute Hospitals NHS Trust, Worcester, UK.
Oral and Maxillofacial Surgery, Worcestershire Acute Hospitals NHS Trust, Worcester, UK
BMJ Case Rep. 2021 May 10;14(5):e239161. doi: 10.1136/bcr-2020-239161.
Trichilemmoma is a benign tumour which arises from the hair follicle root sheath, and commonly occurs in the head and neck area. Malignant transformation and locally aggressive growth of these tumours are very rare. Surgical excision remains the mainstay of management, with scarce evidence for other treatment modalities. We describe our experience of a malignant trichilemmal tumour which demonstrated bony erosion with intracranial extension. Our patient was treated with radical radiotherapy, with a good response at 6 months of follow-up. This case highlights the need to consider malignant potential in recurrent skin lesions, along with the potential for trichilemmoma to erode bone, necessitating the consideration of different treatment modalities.
毛发上皮瘤是一种来源于毛囊根鞘的良性肿瘤，常见于头颈部。这些肿瘤恶性转化和局部侵袭性生长非常罕见。手术切除仍然是主要的治疗方法，其他治疗方式的证据很少。我们描述了一例表现为骨侵蚀伴颅内延伸的恶性毛发上皮瘤的经验。我们的患者接受了根治性放疗，随访 6 个月时反应良好。本病例强调了在复发性皮肤病变中需要考虑恶性潜能，以及毛发上皮瘤侵蚀骨骼的可能性，这需要考虑不同的治疗方式。
