Endemic SARS-CoV-2 Polymorphisms Can Cause a Higher Diagnostic Target Failure Rate than Estimated by Aggregate Global Sequencing Data.
作者信息
Rhoads Daniel D, Plunkett David, Nakitandwe Joy, Dempsey Andrew, Tu Zheng Jin, Procop Gary W, Bosler David, Rubin Brian P, Loeffelholz Michael J, Brock Jay E
机构信息
Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Cepheid, Sunnyvale, California, USA.
出版信息
J Clin Microbiol. 2021 Jul 19;59(8):e0091321. doi: 10.1128/JCM.00913-21.
Abstract
摘要
相似文献
1
Endemic SARS-CoV-2 Polymorphisms Can Cause a Higher Diagnostic Target Failure Rate than Estimated by Aggregate Global Sequencing Data.
J Clin Microbiol. 2021 Jul 19;59(8):e0091321. doi: 10.1128/JCM.00913-21.
2
SARS-CoV-2 variants with T135I nucleocapsid mutations may affect antigen test performance.
Int J Infect Dis. 2022 Jan;114:112-114. doi: 10.1016/j.ijid.2021.11.006. Epub 2021 Nov 7.
3
A SARS-CoV-2 Nucleocapsid Variant that Affects Antigen Test Performance.
J Clin Virol. 2021 Aug;141:104900. doi: 10.1016/j.jcv.2021.104900. Epub 2021 Jun 17.
4
Assessment of two-pool multiplex long-amplicon nanopore sequencing of SARS-CoV-2.
J Med Virol. 2022 Jan;94(1):327-334. doi: 10.1002/jmv.27336. Epub 2021 Sep 23.
5
Clinical Validation of a SARS-CoV-2 Real-Time Reverse Transcription PCR Assay Targeting the Nucleocapsid Gene.
J Appl Lab Med. 2020 Sep 1;5(5):889-896. doi: 10.1093/jalm/jfaa089.
6
SARS-CoV-2 N gene mutations impact detection by clinical molecular diagnostics: reports in two cities in the United States.
Diagn Microbiol Infect Dis. 2021 Nov;101(3):115468. doi: 10.1016/j.diagmicrobio.2021.115468. Epub 2021 Jul 5.
7
SARS-CoV-2 N gene dropout and N gene Ct value shift as indicator for the presence of B.1.1.7 lineage in a commercial multiplex PCR assay.
Clin Microbiol Infect. 2021 Sep;27(9):1353.e1-1353.e5. doi: 10.1016/j.cmi.2021.05.025. Epub 2021 May 24.
8
A rapid, cost-effective tailed amplicon method for sequencing SARS-CoV-2.
BMC Genomics. 2020 Dec 4;21(1):863. doi: 10.1186/s12864-020-07283-6.
9
Comparison of RNA In Situ Hybridization and Immunohistochemistry Techniques for the Detection and Localization of SARS-CoV-2 in Human Tissues.
Am J Surg Pathol. 2021 Jan;45(1):14-24. doi: 10.1097/PAS.0000000000001563.
10
Assessing oligonucleotide designs from early lab developed PCR diagnostic tests for SARS-CoV-2 using the PCR_strainer pipeline.
J Clin Virol. 2020 Oct;131:104581. doi: 10.1016/j.jcv.2020.104581. Epub 2020 Aug 21.
引用本文的文献
1
Wastewater Surveillance for SARS-CoV-2 in Northern Italy: An Evaluation of Three Different Gene Targets.
Microorganisms. 2025 Jan 22;13(2):236. doi: 10.3390/microorganisms13020236.
2
SARS-CoV-2 Nucleocapsid Protein Mutations Found in Switzerland Disrupt N-Gene Amplification in Commonly Used Multiplex RT-PCR Assay.
Pathogens. 2023 Nov 24;12(12):1383. doi: 10.3390/pathogens12121383.
3
A mutation responsible for impaired detection by the Xpert SARS-CoV-2 assay independently emerged in different lineages during the SARS-CoV-2 pandemic.
BMC Microbiol. 2023 Jul 17;23(1):190. doi: 10.1186/s12866-023-02924-8.
4
Diagnostics and analysis of SARS-CoV-2: current status, recent advances, challenges and perspectives.
Chem Sci. 2023 May 3;14(23):6149-6206. doi: 10.1039/d2sc06665c. eCollection 2023 Jun 14.
5
Cycle Threshold (Ct) Values of SARS-CoV-2 Detected with the GeneXpert System and a Mutation Associated with Different Target Gene Failure.
Curr Issues Mol Biol. 2023 May 7;45(5):4124-4134. doi: 10.3390/cimb45050262.
6
Deciphering a Case of SARS-CoV-2 Gene Dropout With the Xpert Xpress Assay.
Ann Lab Med. 2023 Jul 1;43(4):392-394. doi: 10.3343/alm.2023.43.4.392. Epub 2023 Feb 24.
7
Analytical performance of rapid nucleic acid detection assays and routine RT-qPCR assays for detection of SARS-CoV-2 in Shanghai, China in 2022.
Diagn Microbiol Infect Dis. 2023 Feb;105(2):115860. doi: 10.1016/j.diagmicrobio.2022.115860. Epub 2022 Nov 12.
8
Emergence of a mutation in the nucleocapsid gene of SARS-CoV-2 interferes with PCR detection in Canada.
Sci Rep. 2022 Jun 27;12(1):10867. doi: 10.1038/s41598-022-13995-4.
9
Partial ORF1ab Gene Target Failure with Omicron BA.2.12.1.
J Clin Microbiol. 2022 Jun 15;60(6):e0060022. doi: 10.1128/jcm.00600-22. Epub 2022 May 18.
10
Assessment of BIV1-CovIran inactivated vaccine-elicited neutralizing antibody against the emerging SARS-CoV-2 variants of concern.
Clin Microbiol Infect. 2022 Jun;28(6):882.e1-882.e7. doi: 10.1016/j.cmi.2022.02.030. Epub 2022 Mar 3.
本文引用的文献
1
S-Gene Target Failure as a Marker of Variant B.1.1.7 Among SARS-CoV-2 Isolates in the Greater Toronto Area, December 2020 to March 2021.
JAMA. 2021 May 25;325(20):2115-2116. doi: 10.1001/jama.2021.5607.
2
Two-step strategy for the identification of SARS-CoV-2 variant of concern 202012/01 and other variants with spike deletion H69-V70, France, August to December 2020.
Euro Surveill. 2021 Jan;26(3). doi: 10.2807/1560-7917.ES.2021.26.3.2100008.
3
A Novel Point Mutation in the N Gene of SARS-CoV-2 May Affect the Detection of the Virus by Reverse Transcription-Quantitative PCR.
J Clin Microbiol. 2021 Mar 19;59(4). doi: 10.1128/JCM.03278-20.
4
SARS-CoV-2 samples may escape detection because of a single point mutation in the N gene.
Euro Surveill. 2020 Oct;25(39). doi: 10.2807/1560-7917.ES.2020.25.39.2001650.
5
College of American Pathologists (CAP) Microbiology Committee Perspective: Caution Must Be Used in Interpreting the Cycle Threshold (Ct) Value.
Clin Infect Dis. 2021 May 18;72(10):e685-e686. doi: 10.1093/cid/ciaa1199.
6
A Recurrent Mutation at Position 26340 of SARS-CoV-2 Is Associated with Failure of the E Gene Quantitative Reverse Transcription-PCR Utilized in a Commercial Dual-Target Diagnostic Assay.
J Clin Microbiol. 2020 Sep 22;58(10). doi: 10.1128/JCM.01598-20.
Zotero 插件