Department of Cardiovascular Surgery, Yokosuka General Hospital, Uwamachi, Japan.
Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Shimotsuke, Japan.
J Card Surg. 2021 Aug;36(8):2754-2764. doi: 10.1111/jocs.15617. Epub 2021 May 11.
Although elderly patients undergoing surgery for acute type A aortic dissection (ATAAD) is increasing, their physical activities are not fully understood. We report the physical activities and surgical outcomes in elderly patients who underwent ATAAD.
From 2009 to 2019, 103 consecutive patients underwent surgery for ATAAD at our institution. Surgical outcomes along with pre- and postoperative physical activities in 52 elderly patients (≥70 years old) were compared with those in 51 younger patients (<70 years old). Postoperative walking difficulty was defined as taking ≥30 days to regain the ability to walk 200 m postoperatively or as the inability to walk at discharge.
It took longer for elderly patients to regain the ability to walk 100 or 200 m postoperatively. ROC analysis revealed the AUC of the duration for walking 200 m postoperatively as a prognostic indicator for late deaths was 0.878, with the highest accuracy at 30 days (sensitivity = 83.3%, specificity = 91.8%). Hospital mortality within 30 days was 3.8%, and 1-, 3-, and 5-years survival rates were 92%, 84.7%, 84.7%, respectively, for elderly patients, with no significant differences between groups. Cox proportional hazard analysis showed postoperative walking difficulty was an independent risk factor for late mortality in all cohorts (p = .017).
Elderly patients undergoing surgical ATAAD repair showed acceptable surgical outcomes. However, they were more likely to decrease their physical activities postoperatively. Postoperative difficulty in walking was an independent risk factor for the late mortality in patients with ATAAD.
尽管接受急性 A 型主动脉夹层(ATAAD)手术的老年患者数量不断增加,但他们的身体活动情况仍未得到充分了解。我们报告了在我们机构接受 ATAAD 手术的老年患者的身体活动情况和手术结果。
2009 年至 2019 年,我们机构共对 103 例 ATAAD 患者进行了手术。我们比较了 52 例老年患者(≥70 岁)与 51 例年轻患者(<70 岁)的手术结果以及术前和术后的身体活动情况。术后行走困难定义为术后恢复行走 200 米的能力需要≥30 天,或出院时无法行走。
老年患者术后恢复行走 100 米或 200 米的时间更长。ROC 分析显示,术后行走 200 米的时间曲线下面积(AUC)是预测晚期死亡的预后指标,其 AUC 为 0.878,在术后 30 天的准确性最高(敏感性为 83.3%,特异性为 91.8%)。术后 30 天内院内死亡率为 3.8%,老年患者 1 年、3 年和 5 年生存率分别为 92%、84.7%和 84.7%,各组之间无显著差异。Cox 比例风险分析显示,术后行走困难是所有队列中晚期死亡的独立危险因素(p=0.017)。
接受外科 ATAAD 修复的老年患者手术结果可接受。然而,他们术后更可能减少身体活动。术后行走困难是 ATAAD 患者晚期死亡的独立危险因素。