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Maternal obstructive sleep apnea and neonatal birth outcomes in a population based sample.基于人群样本的母体阻塞性睡眠呼吸暂停与新生儿出生结局。
Sleep Med. 2020 Feb;66:233-240. doi: 10.1016/j.sleep.2019.01.019. Epub 2019 Jan 28.
2
The Association Between Obstructive Sleep Apnea Characterized by a Minimum 3 Percent Oxygen Desaturation or Arousal Hypopnea Definition and Hypertension.以最低 3%的血氧饱和度下降或觉醒呼吸暂停定义为特征的阻塞性睡眠呼吸暂停与高血压之间的关联。
J Clin Sleep Med. 2019 Sep 15;15(9):1261-1270. doi: 10.5664/jcsm.7916.
3
The STOP-Bang Questionnaire as a Screening Tool for Obstructive Sleep Apnea in Pregnancy.STOP-Bang 问卷作为妊娠期阻塞性睡眠呼吸暂停的筛查工具。
J Clin Sleep Med. 2019 May 15;15(5):705-710. doi: 10.5664/jcsm.7754.
4
ACOG Practice Bulletin No. 202: Gestational Hypertension and Preeclampsia.美国妇产科医师学会实践公告第 202 号:妊娠期高血压与子痫前期。
Obstet Gynecol. 2019 Jan;133(1):1. doi: 10.1097/AOG.0000000000003018.
5
The prevalence of obstructive sleep apnea and its association with pregnancy-related health outcomes: a systematic review and meta-analysis.阻塞性睡眠呼吸暂停的患病率及其与妊娠相关健康结局的关系:系统评价和荟萃分析。
Sleep Breath. 2019 Jun;23(2):399-412. doi: 10.1007/s11325-018-1714-7. Epub 2018 Sep 25.
6
Screening extremely obese pregnant women for obstructive sleep apnea.对极度肥胖的孕妇进行阻塞性睡眠呼吸暂停筛查。
Am J Obstet Gynecol. 2018 Dec;219(6):613.e1-613.e10. doi: 10.1016/j.ajog.2018.09.001. Epub 2018 Sep 11.
7
Maternal sleep during pregnancy and poor fetal outcomes: A scoping review of the literature with meta-analysis.孕期母体睡眠与不良胎儿结局:文献综述与荟萃分析
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8
Association between Sleep-Disordered Breathing during Pregnancy and Maternal and Fetal Outcomes: An Updated Systematic Review and Meta-Analysis.孕期睡眠呼吸障碍与母婴结局之间的关联:一项更新的系统评价和荟萃分析。
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9
Predictors of sleep-disordered breathing in pregnancy.妊娠睡眠呼吸障碍的预测因素。
Am J Obstet Gynecol. 2018 May;218(5):521.e1-521.e12. doi: 10.1016/j.ajog.2018.01.031. Epub 2018 Feb 2.
10
The intrapartum and perinatal risks of sleep-disordered breathing in pregnancy: a systematic review and metaanalysis.孕期睡眠障碍呼吸的分娩期和围产期风险:系统评价和荟萃分析。
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妊娠期阻塞性睡眠呼吸暂停:我们睡眠妊娠诊所的早期经验。

Obstructive Sleep Apnea in Pregnancy: Early Lessons From Our Sleep Pregnancy Clinic.

机构信息

Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin,

Department of Biology, University of Wisconsin-Madison, Madison, Wisconsin.

出版信息

WMJ. 2021 Apr;120(1):34-40.

PMID:33974763
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9527631/
Abstract

PROBLEM CONSIDERED

Obstructive sleep apnea (OSA) is underdiagnosed during pregnancy, but there is strong theoretical and some empiric evidence that treatment may improve obstetric outcomes. Barriers to screening, testing, and treatment are common during pregnancy. The goal of this described intervention was to reduce these barriers and improve detection of OSA in pregnancy.

METHODS

Representatives from sleep medicine and perinatology established a cross-disciplinary, collaborative Sleep Pregnancy Clinic offering a streamlined referral process for multimodal screening, testing, and treatment of OSA during pregnancy. This is a retrospective analysis of data from the clinic's first 19 months.

RESULTS

Between June 2017 and December 2018, 134 pregnant women were referred for OSA testing. Sixty-three (47.0%) completed objective sleep testing, and 38 (60.3%) of the women who completed testing met diagnostic criteria for OSA. This intervention resulted in a statistically significant increase in the number of diagnostic sleep apnea tests performed (average 22.4 tests per year pre-intervention, 77 per year post-intervention [  = 0.0012]).

DISCUSSION AND CONCLUSIONS

Despite a streamlined referral pipeline, completion rates of OSA testing in pregnant women remained below 50%. However, the overall number of women referred and who completed testing increased significantly during this time period. Of those who completed testing, the majority were diagnosed with OSA. Since starting this clinic, we have created resources to familiarize patients with the equipment and worked to reduce other barriers. Assessment of these interventions and the impact of treatment on obstetric outcomes is ongoing, as is assessment of reasons women do not complete diagnostic testing.

摘要

问题考虑

阻塞性睡眠呼吸暂停(OSA)在怀孕期间诊断不足,但有强有力的理论和一些经验证据表明,治疗可能改善产科结局。在怀孕期间,筛查、检测和治疗的障碍很常见。本研究中描述的干预措施旨在减少这些障碍,并提高对妊娠期间 OSA 的检测率。

方法

睡眠医学和围产医学的代表成立了一个跨学科的、协作的睡眠妊娠诊所,为妊娠期间 OSA 的多模式筛查、检测和治疗提供了一个简化的转诊流程。这是对诊所前 19 个月数据的回顾性分析。

结果

2017 年 6 月至 2018 年 12 月期间,有 134 名孕妇被转介进行 OSA 检测。63 名(47.0%)完成了客观睡眠测试,38 名(60.3%)完成测试的女性符合 OSA 的诊断标准。这一干预措施导致诊断性睡眠呼吸暂停测试的数量显著增加(干预前平均每年进行 22.4 次测试,干预后每年 77 次[=0.0012])。

讨论和结论

尽管转诊流程简化,但仍有 50%以下的孕妇完成 OSA 检测。然而,在此期间,被转介并完成测试的女性人数显著增加。在完成测试的女性中,大多数被诊断为 OSA。自从开设这个诊所以来,我们已经创建了资源来让患者熟悉设备,并努力减少其他障碍。正在评估这些干预措施以及治疗对产科结局的影响,还在评估女性不完成诊断性测试的原因。