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孕期母体睡眠与不良胎儿结局:文献综述与荟萃分析

Maternal sleep during pregnancy and poor fetal outcomes: A scoping review of the literature with meta-analysis.

机构信息

Mother's Babies and Families Research Group, School of Nursing and Midwifery, University of South Australia, Adelaide, 5001, SA, Australia.

Behaviour-Brain-Body Research Centre, School of Psychology, Social Work and Social Policy, University of South Australia, Adelaide, SA, 5001, Australia.

出版信息

Sleep Med Rev. 2018 Oct;41:197-219. doi: 10.1016/j.smrv.2018.03.004. Epub 2018 Mar 27.

Abstract

There is a wealth of evidence to say that sleep impacts maternal health during pregnancy, however, little has been published on fetal health and maternal sleep. This scoping review summarises current literature on maternal sleep including sleep disordered breathing, sleep quality, sleep duration and supine sleep position, as these relate to fetal outcomes specifically birth weight, growth, preterm birth and stillbirth. An overall interpretation of the studies evaluated shows that events occurring during maternal sleep such as obstructive sleep apnea, sleep disruption and sleep position may have a negative effect on the fetus resulting in altered growth, gestational length and even death. These effects are biologically and physically plausible. In conclusion, there is limited and often conflicting information on maternal sleep and fetal outcomes. However, existing evidence suggests that this is an important area for future research. This area is ripe for investigation if there is to be reduction in the physical, emotional, and financial burden of poor fetal outcomes related to maternal sleep.

摘要

有大量证据表明,睡眠会影响孕妇的健康,但关于胎儿健康和母亲睡眠的研究却很少。本范围综述总结了目前关于母亲睡眠的文献,包括睡眠障碍性呼吸、睡眠质量、睡眠时间和仰卧睡眠姿势,因为这些与胎儿的结果(特别是出生体重、生长、早产和死产)有关。对评估的研究进行的总体解释表明,母亲睡眠期间发生的事件,如阻塞性睡眠呼吸暂停、睡眠中断和睡眠姿势,可能对胎儿产生负面影响,导致生长改变、妊娠时间改变,甚至死亡。这些影响在生物学和物理上是合理的。总之,关于母亲睡眠和胎儿结果的信息有限,而且往往相互矛盾。然而,现有证据表明,这是未来研究的一个重要领域。如果要减少与母亲睡眠相关的不良胎儿结果带来的身体、情感和经济负担,那么这一领域就需要进行调查。

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