School of Pharmaceutical Science and Technology, Tianjin University, 92 Weijin Road, Tianjin, 300092, People's Republic of China.
Department of Analytical Research and Development, Merck & Co., Inc. Boston, MA, 02115, United States.
Phytochemistry. 2021 Aug;188:112792. doi: 10.1016/j.phytochem.2021.112792. Epub 2021 May 8.
Seven undescribed bianthrones, the brevianthrones, together with two known anthraquinones, were isolated from the plant-derived fungus Colletotrichum brevisporum, obtained from the plant Piper sarmentosum Roxb., collected in Guangxi, China. This is the first report of the isolation of bianthrones from the Colletotrichum genus. The structures of the compounds were elucidated by a combination of NMR and MS spectroscopic analysis, while the absolute configurations were determined by X-ray crystallography and by simulation of ECD spectra.
从中国广西采集的植物 Piper sarmentosum Roxb. 中分离出的植物源真菌 Colletotrichum brevisporum 中分离出了 7 种未被描述的双蒽酮，以及 2 种已知的蒽醌。这是首次从 Colletotrichum 属中分离出双蒽酮。通过 NMR 和 MS 光谱分析相结合的方法阐明了化合物的结构，而通过 X 射线晶体学和 ECD 光谱模拟确定了它们的绝对构型。
