Petrás P, Zdrazílek J, Srámová H, Masková L
Institute of Hygiene and Epidemiology, Prague, Czechoslovakia.
J Hyg Epidemiol Microbiol Immunol. 1988;32(1):59-69.
Tests for enterotoxins A, B, C, D, E and TSST-1 production were carried out on 775 S. aureus strains isolated from various sources (50 mothers and neonates studied periodically, mothers and infants treated for various acute inflammatory conditions, members of hospital staff, environmental swabs) during the period 1981-1983 at a maternity ward chosen for a 3-year systematic study and on additional 97 isolates obtained in 1985 from another maternity ward. This had contributed to a better classification of strains within certain phage type groups. It was found that the distribution of S. aureus types in the particular sub-sets varied, depending on the source of isolates. At the maternity ward followed for 3 years there was a clear-cut trend towards the spread of phage-untypable isolates producing enterotoxin C whereas at ward examined for comparative purposes B enterotoxin producers of phage type 95 were predominant. The tests for enterotoxigenicity has also proved to be useful as the epidemiological marker characterizing the predominantly circulating S. aureus strain. It has been confirmed that the majority role in the spread of maternity-ward-staphylococci is played by the neonates and the factors of hospital environment.
对1981 - 1983年期间从不同来源（50名接受定期研究的母亲和新生儿、因各种急性炎症疾病接受治疗的母亲和婴儿、医院工作人员、环境拭子）分离出的775株金黄色葡萄球菌菌株进行了A、B、C、D、E型肠毒素和中毒性休克综合征毒素-1（TSST-1）产生情况的检测。这些菌株来自一个被选作进行为期3年系统研究的产科病房，另外还对1985年从另一个产科病房获得的97株分离株进行了检测。这有助于对某些噬菌体类型组内的菌株进行更好的分类。结果发现，金黄色葡萄球菌类型在特定亚组中的分布因分离株来源而异。在随访3年的产科病房，产生肠毒素C的噬菌体不可分型分离株有明显的传播趋势，而在用于比较目的的病房中，噬菌体95型的B型肠毒素产生菌占主导地位。肠毒素产生能力的检测也已被证明可作为表征主要流行的金黄色葡萄球菌菌株的流行病学标志物。已证实，新生儿和医院环境因素在产科病房葡萄球菌传播中起主要作用。
