Research Center for Physical Fitness and Health Promotion of Adolescent, Guangzhou Sport University, Guangzhou, China -
Department of Sports and Health, Guangzhou Sport University, Guangzhou, China -
J Sports Med Phys Fitness. 2021 May;61(5):743-752. doi: 10.23736/S0022-4707.20.11329-X.
This systematic review with meta-analysis aimed to quantify the effectiveness of high-intensity interval training (HIIT) on the cardiometabolic health of obese children and adolescents.
Relevant articles were sourced from PubMed, Embase, the Web of Science, EBSCO, the Cochrane Library and China National Knowledge Infrastructure (CNKI). Randomized controlled trials were included if they employed participants aged 7-19 years. Outcomes included fasting glucose (FG), fasting insulin (FI), homeostasis model assessment-insulin resistance (HOMA-IR), high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c), triacylglycerol (TG), total cholesterol (TC), systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured at baseline and postintervention and compared with those in the control group. Data analysis and synthesis were completed by Revman 5.3 software and Stata 12.0 software (StataCorp LLC., College Station, TX, USA).
Eight trials involving 379 participants were identified. HIIT significantly decreased the FI, HOMA-IR, TC, TG, LDL-c and SBP in participants with obesity. With regard to changes in blood glucose and lipids, participants who underwent HIIT showed great improvement in FI (mean difference: -3.09 µU/mL, 95% confidence interval [CI] -3.71 to -2.46, P<0.0001), HOMA-IR (mean difference: -0.64, 95% CI -0.82 to -0.46, P<0.0001), TG (mean difference: -0.21 mmol/L, 95% CI -0.31 to -0.10, P<0.0001) and LDL-c (mean difference: -0.35 mmol/L, 95% CI -0.48 to -0.22, P<0.001) than the control group. Similar results were found for SBP (mean difference: -3.61 mmHg, 95% CI -5.85 to -1.37, P=0.002). However, no significant differences in changes in FG, HDL-c and DBP were observed between HIIT and control groups.
HIIT can produce a positive effect on cardiometabolic risk factors in obese children and adolescents. HIIT may be an alternative and effective training method for managing childhood obesity.
本系统评价和荟萃分析旨在量化高强度间歇训练（HIIT）对肥胖儿童和青少年心脏代谢健康的有效性。
从 PubMed、Embase、Web of Science、EBSCO、Cochrane 图书馆和中国知网（CNKI）中获取相关文章。如果参与者年龄在 7-19 岁，则纳入随机对照试验。如果干预组和对照组之间在空腹血糖（FG）、空腹胰岛素（FI）、胰岛素抵抗评估指数（HOMA-IR）、高密度脂蛋白胆固醇（HDL-c）、低密度脂蛋白胆固醇（LDL-c）、三酰甘油（TG）、总胆固醇（TC）、收缩压（SBP）和舒张压（DBP）方面有差异，则认为具有统计学意义。采用 Revman 5.3 软件和 Stata 12.0 软件（StataCorp LLC.，College Station，TX，USA）进行数据分析和综合。
确定了八项涉及 379 名参与者的试验。HIIT 可显著降低肥胖参与者的 FI、HOMA-IR、TC、TG、LDL-c 和 SBP。关于血糖和血脂的变化，接受 HIIT 的参与者的 FI（平均差异：-3.09µU/mL，95%置信区间 [CI] -3.71 至 -2.46，P<0.0001）、HOMA-IR（平均差异：-0.64，95% CI -0.82 至 -0.46，P<0.0001）、TG（平均差异：-0.21mmol/L，95% CI -0.31 至 -0.10，P<0.0001）和 LDL-c（平均差异：-0.35mmol/L，95% CI -0.48 至 -0.22，P<0.001）的变化显著优于对照组。SBP（平均差异：-3.61mmHg，95% CI -5.85 至 -1.37，P=0.002）也有类似的结果。然而，HIIT 组和对照组在 FG、HDL-c 和 DBP 方面的变化无显著差异。
HIIT 对肥胖儿童和青少年的心脏代谢危险因素有积极影响。HIIT 可能是管理儿童肥胖的一种替代和有效的训练方法。
