Rosenhall U, Johansson E, Gillberg C
Department of Audiology and Otolaryngology, Sahlgren's Hospital, Göteborg, Sweden.
J Laryngol Otol. 1988 May;102(5):435-9. doi: 10.1017/s0022215100105286.
Eleven children with infantile autism or autistic-like conditions were examined with oculomotor tests and with auditory brainstem response audiometry. Measurements of voluntary, horizontal non-predictable saccades showed that the eye motor function was abnormal in six (55 per cent) of the eleven patients. The saccades were hypometric in all six instances and the saccadic velocity was reduced in four instances. The abnormalities observed are consistent with brain dysfunction, in most cases probably indicating pontocerebellar involvement. In five instances ABR was found to be abnormal which indicates brainstem dysfunction. Oculomotor dysfunction and/or ABR abnormality was observed in eight (73 per cent) of the patients studied.
对11名患有婴儿自闭症或类自闭症病症的儿童进行了眼动测试和听觉脑干反应听力测定。对随意性、水平不可预测性扫视的测量表明,11名患者中有6名(55%)的眼动功能异常。在所有6例中扫视幅度减小,4例中扫视速度降低。观察到的异常与脑功能障碍一致,在大多数情况下可能表明脑桥小脑受累。在5例中发现听觉脑干反应异常,这表明脑干功能障碍。在所研究的患者中,8名(73%)出现了眼动功能障碍和/或听觉脑干反应异常。