Bozkanat Kubra M, West Natalie E, Ladores Sigrid, Montemayor Kristina, Tupayachi Ortiz Maria Gabriela, Christianson Mindy, Jain Raksha
Department of Pediatrics University of Texas Southwestern Medical Center Dallas TX USA.
Department of Internal Medicine Johns Hopkins University Baltimore MD USA.
Respirol Case Rep. 2021 May 7;9(6):e00755. doi: 10.1002/rcr2.755. eCollection 2021 Jun.
Catamenial haemoptysis, the expectoration of blood during menses, has not been extensively reported in the cystic fibrosis (CF) literature. We describe four cases (age range: 25-34 years) of catamenial haemoptysis across four CF centres in the United States. These cases may represent thoracic endometriosis versus hormonal fluctuations in airway inflammation or infection resulting in bronchial artery bleeding. We identify common and nuanced management strategies including use of pro-coagulants, hormone contraceptives, anti-inflammatories, bronchial artery embolization, and use of the newer cystic fibrosis transmembrane conductance regulator (CFTR) modulators.
经期咯血，即在月经期间咯血，在囊性纤维化（CF）文献中尚未有广泛报道。我们描述了美国四个CF中心的4例（年龄范围：25 - 34岁）经期咯血病例。这些病例可能代表胸段子宫内膜异位症，也可能是气道炎症或感染中的激素波动导致支气管动脉出血。我们确定了常见且细微的管理策略，包括使用促凝血剂、激素避孕药、抗炎药、支气管动脉栓塞以及使用新型囊性纤维化跨膜传导调节因子（CFTR）调节剂。
