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继发性自发性气胸的保守治疗与侵入性治疗:一项回顾性队列研究

Conservative versus invasive management of secondary spontaneous pneumothorax: a retrospective cohort study.

作者信息

Gerhardy Benjamin Carl, Simpson Graham

机构信息

Department of Respiratory Medicine Cairns Hospital Cairns QLD Australia.

出版信息

Acute Med Surg. 2021 May 7;8(1):e663. doi: 10.1002/ams2.663. eCollection 2021 Jan-Dec.

Abstract

AIM

Hospitalization, often with intervention, is the recommended management algorithm by multiple international respiratory societies for management of a secondary spontaneous pneumothorax (SSP). Over recent years we adopted a conservative approach to SSPs. We undertook a retrospective cohort study of SSP to establish the safety profile of a conservative approach for these previously unstudied patients.

METHODS

We reviewed all cases of SSP presenting to our institution from 2012 to 2019 using the 2010 British Thoracic Society definition of an SSP. Age, gender, smoking status, underlying lung disease, pneumothorax size estimate (using the Collins method), nature of intervention, inpatient duration, and any additional complications were recorded. The χ-test and Mann-Whitney -test were used for comparison of categorical variables and categorical/continuous variables, respectively.

RESULTS

Eighty-two cases were included in the final analysis. Of them, 64 had an interpleural distance at the hilum of 1cm or greater, meeting British Thoracic Society criteria for a pleural intervention. Of these 64 patients, 25 (39%) were managed conservatively. No patient managed conservatively required a subsequent intervention. When stratified for conservative or invasive management, there was no significant difference in age, gender, smoking status, or presence of underlying lung disease between the groups. There was a significant difference in size of the pneumothorax with conservative management having smaller pneumothoraces (37% versus 54%,  < 0.001) and a shorter inpatient stay (conservative, 7.9 days; intercostal catheter, 9 days;  = 0.004).

CONCLUSION

We have demonstrated success with conservative management of SSPs where a significant proportion of them met accepted criteria for a pleural intervention.

摘要

目的

住院治疗(通常需进行干预)是多个国际呼吸学会推荐的继发性自发性气胸(SSP)管理算法。近年来,我们对SSP采取了保守治疗方法。我们对SSP进行了一项回顾性队列研究,以确定这种保守治疗方法对这些此前未被研究过的患者的安全性。

方法

我们使用2010年英国胸科学会对SSP的定义,回顾了2012年至2019年在我们机构就诊的所有SSP病例。记录了年龄、性别、吸烟状况、潜在肺部疾病、气胸大小估计(使用柯林斯方法)、干预性质、住院时间以及任何其他并发症。分别使用χ检验和曼-惠特尼检验来比较分类变量和分类/连续变量。

结果

最终分析纳入了82例病例。其中,64例肺门处胸膜腔间距为1厘米或更大,符合英国胸科学会胸膜干预标准。在这64例患者中,25例(39%)接受了保守治疗。接受保守治疗的患者均无需后续干预。按保守或侵入性治疗分层时,两组在年龄、性别、吸烟状况或潜在肺部疾病的存在方面无显著差异。气胸大小存在显著差异,保守治疗的气胸较小(37%对54%,<0.001),住院时间较短(保守治疗,7.9天;肋间导管引流,9天;=0.004)。

结论

我们已证明对SSP进行保守治疗是成功的,其中很大一部分患者符合胸膜干预的公认标准。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d42/8103887/03a95ef855bd/AMS2-8-e663-g002.jpg

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