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自发性气胸;急诊治疗、并发症和结局的多中心回顾性分析。

Spontaneous pneumothorax; a multicentre retrospective analysis of emergency treatment, complications and outcomes.

机构信息

Centre for Clinical Research in Emergency Medicine, Harry Perkins Institute of Medical Research, Perth, Western Australia, Australia; Department of Emergency Medicine, Royal Perth Hospital, Perth, Western Australia, Australia; Emergency Medicine, University of Western Australia, Perth, Western Australia, Australia.

出版信息

Intern Med J. 2014 May;44(5):450-7. doi: 10.1111/imj.12398.

Abstract

BACKGROUND

Spontaneous pneumothorax can be managed initially by observation, aspiration or chest drain insertion.

AIMS

To determine the clinical features of spontaneous pneumothorax in patients presenting to the emergency department (ED), interventions, outcomes and potential risk factors for poor outcomes after treatment.

METHODS

Retrospective chart review from ED of three major referral and two general hospitals in Australia of presentations with primary spontaneous pneumothorax (PSP) or secondary spontaneous pneumothorax (SSP). Main outcomes were prolonged air leak (>5 days) and pneumothorax recurrence within 1 year.

RESULTS

We identified 225 people with PSP and 98 with SSP. There were no clinical tension pneumothoraces with hypotension. Hypoxaemia (haemoglobin oxygen saturation measured by pulse oximetry ≤92%) occurred only in SSP and in older patients (age >50 years) with PSP. Drainage was performed in 150 (67%) PSP and 82 (84%) SSP. Prolonged air leak occurred in 16% (95% confidence interval 10-23%) of PSP and 31% (21-42%) of SSP. Independent risk factors for prolonged drainage were non-asthma SSP and pneumothorax size >50%. Complications were recorded in 11% (7.5-16%) of those having drains inserted. Recurrences occurred in 5/91 (5%, 1.8-12%) of those treated without drainage versus 40/232 (17%, 13-23%) of those treated by drainage, of which half occurred in the first month after drainage.

CONCLUSION

Pneumothorax drainage is associated with substantial morbidity including prolonged air leak. As PSP appears to be well tolerated in younger people even with large pneumothoraces, conservative treatment in this subgroup may be a viable option to improve patient outcomes, but this needs to be confirmed in a clinical trial.

摘要

背景

自发性气胸可通过观察、抽吸或胸腔引流来初步治疗。

目的

确定急诊就诊的自发性气胸患者的临床特征、干预措施、结局以及治疗后预后不良的潜在危险因素。

方法

回顾性分析澳大利亚三家转诊医院和两家综合医院急诊科的原发性自发性气胸(PSP)或继发性自发性气胸(SSP)患者的病历资料。主要结局为气胸迁延不愈(>5 天)和 1 年内气胸复发。

结果

共纳入 225 例 PSP 和 98 例 SSP 患者。虽有气胸,但无张力性气胸或低血压。低氧血症(脉搏血氧饱和度仪测量的血红蛋白氧饱和度≤92%)仅见于 SSP 和 PSP 老年患者(>50 岁)。150 例(67%)PSP 和 82 例(84%)SSP 患者行引流术。PSP 中迁延不愈的发生率为 16%(95%置信区间为 10%-23%),SSP 中为 31%(21%-42%)。非哮喘性 SSP 和气胸范围>50%是迁延不愈的独立危险因素。引流组有 11%(7.5%-16%)的患者出现并发症。未引流组中有 5/91(5%,1.8%-12%)例复发,引流组中有 40/232(17%,13%-23%)例复发,其中一半发生在引流后 1 个月内。

结论

气胸引流会导致严重的发病率,包括气胸迁延不愈。对于年轻患者,即使气胸范围较大,PSP 似乎也能很好耐受,因此在该亚组患者中采用保守治疗可能是改善患者结局的可行方案,但这需要在临床试验中进一步证实。

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