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逆行肾内手术、顺行输尿管镜检查和腹腔镜输尿管切开取石术治疗直径大于1.5 cm的嵌顿性近端输尿管结石的比较评估

Comparative evaluation of retrograde intrarenal surgery, antegrade ureterorenoscopy and laparoscopic ureterolithotomy in the treatment of impacted proximal ureteral stones larger than 1.5 cm.

作者信息

Güler Yavuz, Erbin Akif

机构信息

Department of Urology, Private Safa Hospital, Istanbul, Turkey.

Department of Urology, Haseki Traning and Research Hospital, Haseki, Turkey.

出版信息

Cent European J Urol. 2021;74(1):57-63. doi: 10.5173/ceju.2021.0174.R1. Epub 2021 Jan 23.

Abstract

INTRODUCTION

The aim of this article was to compare retrograde intrarenal surgery (RIRS), antegrade ureterorenoscopy (URS), and laparoscopic ureterolithotomy (LU) for impacted proximal ureter stones larger than 1.5 cm in terms of operative data, success, complications, auxiliary treatment rates, and visual analog scale (VAS) scores.

MATERIAL AND METHODS

Medical records of patients undergoing RIRS, antegrade URS, or LU were retrospectively reviewed. After exclusion criteria, 122 patients were included in advanced analyses. Patients were divided into 3 groups as RIRS (n = 43), antegrade URS (n = 38) and LU (n = 41).

RESULTS

Operation time was shortest in the antegrade URS and hospitalization time was shortest in the RIRS group (p <0.001 and p <0.001, respectively). VAS scores were lowest in the RIRS group and highest in the LU group (p <0.001). Success (complete stone clearance) rates were 83.7%, 97.4%, and 97.5% in the RIRS, antegrade URS, and LU groups, respectively (p <0.001). Auxiliary treatment rates in the RIRS, antegrade URS, and LU groups were 19.1%, 2.6%, and 4.7%, respectively (p <0.001). Although there was no significant difference in terms of general complication rates, grade II complication rate (blood transfusion) was significantly higher in the antegrade URS group and grade IVb complication rate (urosepsis) was higher in the RIRS group according to the modified Clavien-Dindo classification system (p = 0.007 and p = 0.02, respectively).

CONCLUSIONS

Antegrade URS or LU are more logical options than RIRS for the treatment of large impacted proximal ureter stones. Between antegrade URS or LU, antegrade URS seems to be a more reasonable option due to its less invasive nature.

摘要

引言

本文旨在比较逆行肾内手术(RIRS)、顺行输尿管镜检查(URS)和腹腔镜输尿管切开取石术(LU)治疗直径大于1.5 cm的近端输尿管嵌顿结石的手术数据、成功率、并发症、辅助治疗率及视觉模拟评分(VAS)。

材料与方法

回顾性分析接受RIRS、顺行URS或LU治疗的患者的病历。根据排除标准,122例患者纳入进一步分析。患者分为3组:RIRS组(n = 43)、顺行URS组(n = 38)和LU组(n = 41)。

结果

顺行URS组手术时间最短,RIRS组住院时间最短(分别为p <0.001和p <0.001)。RIRS组VAS评分最低,LU组最高(p <0.001)。RIRS组、顺行URS组和LU组的成功率(结石完全清除率)分别为83.7%、97.4%和97.5%(p <0.001)。RIRS组、顺行URS组和LU组的辅助治疗率分别为19.1%、2.6%和4.7%(p <0.001)。根据改良Clavien-Dindo分类系统,尽管总体并发症发生率无显著差异,但顺行URS组II级并发症发生率(输血)显著更高,RIRS组IVb级并发症发生率(尿脓毒症)更高(分别为p = 0.007和p = 0.02)。

结论

对于大型近端输尿管嵌顿结石的治疗,顺行URS或LU比RIRS更合理。在顺行URS和LU之间,由于其侵入性较小,顺行URS似乎是更合理的选择。

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