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经皮肾镜碎石术与逆行输尿管软镜碎石术治疗 1.5cm 或以上嵌顿性上段输尿管结石的对比研究

Comparative study between antegrade flexible ureteroscopy and reterograde intrarenal surgery in the management of impacted upper ureteric stones 1.5 cm or larger.

机构信息

Department of Urology, Benha University Hospital, Faculty of Medicine, Benha University, Farid Nada Street, Benha, Egypt.

出版信息

World J Urol. 2023 Dec;41(12):3731-3736. doi: 10.1007/s00345-023-04672-w. Epub 2023 Nov 3.

Abstract

OBJECTIVE

To prospectively investigate the safety and efficacy of antegrade flexible ureteroscopy (FURS) with the following criteria (supine, ultrasonic guided puncture through lower calyx with 14 fr tract, tubeless) versus retrograde intrarenal surgery (RIRS) in the management of large impacted upper ureteric stones ≥ 1.5 cm.

PATIENTS AND METHODS

This study recruited 61 patients with single large impacted upper ureteric stone of ≥ 1.5 cm. The patients were randomly allocated to two groups. Group A, included 31 patients who treated by antegrade FURS, all patients were put in supine modified galadako Valdivia position and the renal access is reached by ultrasonic guided puncture through the lower calyx with dilatation upto 14 fr to insert ureteric access sheath and all cases were tubless with JJ stent insertion. Group B, included 30 patients who were treated by RIRS with JJ stent insertion. Stone fragmentation was done by holmium laser in both group.

RESULTS

Group A was significantly associated with higher proportion of SFR (90.3%) compared to Group B (70%) (p = 0.046). Group B was significantly associated with shorter operative time and fluoroscopy time in comparison with Group A (p < 0.001). No significant differences were found between studied groups regarding bleeding (p = 0.238). Urosepsis showed significantly higher proportion associated with retrograde approach when compared to antegrade approach (p = 0.024).

CONCLUSION

This study showed that antegrade FURS is safe and more effective than RIRS for the management of large impacted upper ureteric stones ≥ 1.5 cm.

摘要

目的

前瞻性研究顺行软性输尿管镜检查(FURS)以下标准(仰卧位、经下盏超声引导穿刺 14Fr 通道、无管化)与逆行肾内手术(RIRS)治疗单个大的嵌顿性上段输尿管结石≥1.5cm 的安全性和有效性。

患者和方法

本研究纳入了 61 例单发大的嵌顿性上段输尿管结石≥1.5cm 的患者。患者随机分为两组。A 组 31 例患者采用顺行 FURS 治疗,所有患者均采用改良 Galadako-Valdivia 仰卧位,经下盏超声引导穿刺扩张至 14Fr 插入输尿管入鞘,所有病例均无管化并留置 JJ 支架。B 组 30 例患者采用 RIRS 治疗并留置 JJ 支架。两组均采用钬激光碎石。

结果

A 组结石清除率(SFR)显著高于 B 组(90.3%比 70%,p=0.046)。与 A 组相比,B 组的手术时间和透视时间明显更短(p<0.001)。两组间出血无显著差异(p=0.238)。与顺行方法相比,逆行方法发生尿脓毒症的比例显著更高(p=0.024)。

结论

本研究表明,顺行 FURS 治疗大的嵌顿性上段输尿管结石≥1.5cm 安全且效果优于 RIRS。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0706/10693498/fd12c898de27/345_2023_4672_Fig1_HTML.jpg

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