Elsman Ellen B M, Roorda Leo D, Crins Martine H P, Boers Maarten, Terwee Caroline B
Department of Epidemiology and Data Science, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Public Health research institute, de Boelelaan 1089a, 1081 HV, Amsterdam, the Netherlands.
Amsterdam Rehabilitation Research Center | Reade, Amsterdam, the Netherlands.
J Patient Rep Outcomes. 2021 May 12;5(1):38. doi: 10.1186/s41687-021-00314-0.
To add context to the impact of medical conditions, it is important to interpret and compare health outcomes across studies and populations. We aimed to determine Dutch reference values for the Patient-Reported Outcomes Measurement Information System Scale v1.2 - Global Health (PROMIS-GH).
The PROMIS-GH, also referred to as PROMIS-10, was completed by 4370 Dutch persons, representative for the 2016 Dutch population. T-scores for the mental health (GMH) and physical health (GPH) subscales, and their shorter two-item subscales, were calculated for the entire population, age groups and gender. T-scores for GMH and GPH were compared to the US reference population, representative for the 2000 US general population. Interpretability thresholds for poor, fair, good, very good and excellent GPH and GMH were calculated based on T-scores of participants, which were categorized into five groups based on their response to item Global01. For each group the mean GPH and GMH T-score was calculated and the midpoint between two adjacent means was identified, resulting in thresholds. Thresholds based on the Dutch data were compared to US thresholds.
The Dutch population had a GMH T-score of 44.7 and a GPH T-score of 45.2, both substantially worse than the US reference population T-score of 50. Lower T-scores were also found for age-range and gender subpopulations. Dutch GMH and GPH interpretability thresholds were mostly not substantially different compared to the US thresholds, although the Dutch threshold between fair and poor mental health was considerably higher (29 vs. 38).
This study reports reference values for the PROMIS-GH scale for the Dutch general population, including age-range and gender subpopulations. These reference values provide an important tool for healthcare professionals and researchers to better evaluate and interpret patient-reported mental health and physical health. Scores are notably worse than the US reference values. The exact reason for this remains subject for further research, although possibilities for the differences are discussed, including the presence of differential item functioning and the representativeness and recentness of the data.
为了更好地理解疾病状况的影响，对不同研究和人群的健康结果进行解读和比较非常重要。我们旨在确定荷兰人群中患者报告结局测量信息系统量表v1.2 - 总体健康（PROMIS - GH）的参考值。
4370名具有2016年荷兰人口代表性的荷兰人完成了PROMIS - GH（也称为PROMIS - 10）。计算了整个人口、年龄组和性别的心理健康（GMH）和身体健康（GPH）子量表及其较短的两项子量表的T分数。将GMH和GPH的T分数与代表2000年美国普通人群的美国参考人群进行比较。根据参与者的T分数计算出GPH和GMH在差、一般、好、很好和优秀水平的可解释性阈值，这些参与者根据他们对条目Global01的回答被分为五组。计算每组的平均GPH和GMH T分数，并确定两个相邻平均值之间的中点，从而得出阈值。将基于荷兰数据的阈值与美国阈值进行比较。
荷兰人群的GMH T分数为44.7，GPH T分数为45.2，均显著低于美国参考人群的T分数50。在年龄范围和性别亚人群中也发现了较低的T分数。尽管荷兰在一般和差的心理健康之间的阈值明显更高（29对38），但荷兰GMH和GPH的可解释性阈值与美国阈值大多没有实质性差异。
本研究报告了荷兰普通人群以及年龄范围和性别亚人群中PROMIS - GH量表的参考值。这些参考值为医疗保健专业人员和研究人员更好地评估和解读患者报告的心理健康和身体健康提供了重要工具。分数明显低于美国参考值。尽管讨论了差异存在的可能性，包括项目功能差异以及数据的代表性和时效性，但造成这种情况的确切原因仍有待进一步研究。
