Department of Orthopaedics, Dartmouth-Hitchcock Medical Center, Lebanon, NH, 03766, USA.
Department of Orthopaedics, Geisel School of Medicine At Dartmouth, Hanover, NH, 03755, USA.
Qual Life Res. 2021 Aug;30(8):2339-2348. doi: 10.1007/s11136-021-02812-6. Epub 2021 Mar 16.
To investigate the functioning of the PROMIS-Global Health (PROMIS-GH) across clinical setting, patient age, and medical complexity by evaluating differential item functioning (DIF) within the Global Physical Health (GPH) and Global Mental Health (GMH) domains. To our knowledge, no study demonstrates lack of differential item functioning (DIF) for PROMIS-GH across these populations. We hypothesize that the PROMIS-GH domains of GMH and GPH will perform similarly when compared across these populations.
Seven thousand nine hundred and seventy four complete PROMIS Global Health measures were retrospectively analyzed using the 'Lordif' package on the R platform. DIF was investigated for both GMH and GPH across clinical environment (Orthopedic Surgery, Family Medicine, & Internal Medicine), age group (≤ 53, > 53-66, > 66), and Charlson Comorbidity Index (CCI:0, CCI:1, CCI:2 +) using quasi Monte Carlo estimation. To assess the significance of DIF, Wald tests were used with the Benjamini & Hochberg procedure.
No items contained in the GMH or GPH demonstrated DIF across age groups, medical complexity, or clinical environment.
Items assessing the domains of GMH and GPH within the PROMIS-GH function comparably across treatment setting, age category, and medical comorbidities. The PROMIS-Global Health holds potential to facilitate interdisciplinary patient care and patient optimization prior to surgical intervention.
通过评估全球生理健康（GPH）和全球心理健康（GMH）领域内的差异项目功能（DIF），研究 PROMIS-Global Health（PROMIS-GH）在临床环境、患者年龄和医疗复杂性方面的功能。据我们所知，没有研究表明 PROMIS-GH 在这些人群中存在差异项目功能（DIF）。我们假设，当比较这些人群时，PROMIS-GH 的 GMH 和 GPH 领域将表现出相似的性能。
使用 R 平台上的“Lordif”包对 7974 份完整的 PROMIS 全球健康测量数据进行回顾性分析。使用拟蒙特卡罗估计，在临床环境（骨科、家庭医学和内科）、年龄组（≤53 岁、>53-66 岁、>66 岁）和 Charlson 合并症指数（CCI：0、CCI：1、CCI：2+）方面，研究了 GMH 和 GPH 的 DIF。使用 Wald 检验并结合 Benjamini 和 Hochberg 程序评估 DIF 的显著性。
GMH 或 GPH 中没有项目在年龄组、医疗复杂性或临床环境方面存在 DIF。
在治疗环境、年龄类别和医疗合并症方面，PROMIS-GH 中评估 GMH 和 GPH 领域的项目功能相当。PROMIS-Global Health 有可能在手术干预之前促进跨学科的患者护理和患者优化。
