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埃塞俄比亚南部哈迪亚地区霍萨纳镇行政区域内妊娠高血压对母婴结局的影响因素:非匹配病例对照研究。

Determinants of pregnancy-induced hypertension on maternal and foetal outcomes in Hossana town administration, Hadiya zone, Southern Ethiopia: Unmatched case-control study.

机构信息

Department of Nursing College of Medicine and Health Science, Wachemo University, Hossana, Ethiopia.

Department of Public Health College of Medicine and Health Science, Wachemo University, Hossana, Ethiopia.

出版信息

PLoS One. 2021 May 12;16(5):e0250548. doi: 10.1371/journal.pone.0250548. eCollection 2021.

Abstract

BACKGROUND

Globally, 292,982 women die due to the complications of pregnancy and childbirth per year, out of those deaths 85% occurs in Sub Saharan Africa. In Ethiopia, pre-eclampsia accounts for 11% of direct maternal deaths.

OBJECTIVE

To determine maternal and foetal outcomes of pregnancy-induced hypertension among women who gave birth at health facilities in Hossana town administration.

METHODS

Institutional based unmatched case-control study was conducted among women, who gave birth at health facilities from May 20 to October 30, 2018. By using Epi-Info version 7; 207 sample size was estimated, for each case two controls were selected. Two health facilities were selected using a simple random sampling method. Sample sizes for each facility were allocated proportionally. All cleaned & coded data were entered into Epi-info version 3.5.1 and analysis was carried out using SPSS version 20. Multivariate analysis was performed to determine predictors of pregnancy-induced hypertension at a p-value of <0.05.

RESULT

Women between 18 to 41 years old had participated in the study with the mean age of 26.00(SD ±4.42), and 25.87(SD ±5.02) for cases and controls respectively. Out of participants 21(30.4%) among cases and 21(15.2%) among controls had developed at least one complication following delivery. 12 (17.4%) and 8 (5.7%) foetal deaths were found in cases and controls groups respectively whereas 15.6% from cases and 3.6% from controls groups women gave birth to the foetus with intra-uterine growth retardation. Women gravidity AOR = 0.32 [95% CI (0.12 0.86)], Previous history of pregnancy-induced hypertension AOR = 22.50 [95% CI (14.95 16.52)] and educational status AOR = 0.32[95% CI (0.12, 0.85)] were identified as predictor of pregnancy-induced hypertension.

CONCLUSION

Women with a previous history of pregnancy-induced hypertension had increased risk of developing pregnancy-induced hypertension, whilst ≥ 3 previous pregnancies and informal educational status decrease odds of developing pregnancy-induced hypertension.

摘要

背景

全球每年有 292982 名妇女死于妊娠和分娩并发症,其中 85%发生在撒哈拉以南非洲。在埃塞俄比亚,子痫前期占直接产妇死亡的 11%。

目的

确定霍萨纳镇行政区域内医疗机构分娩的孕妇妊娠高血压的母婴结局。

方法

这是一项在 2018 年 5 月 20 日至 10 月 30 日期间在医疗机构分娩的妇女中进行的基于机构的非匹配病例对照研究。采用 Epi-Info 版本 7;估计了 207 名样本量,每个病例选择 2 名对照。采用简单随机抽样法选择了 2 个卫生机构。每个机构的样本量按比例分配。所有清理和编码后的数据均输入 Epi-info 版本 3.5.1,并使用 SPSS 版本 20 进行分析。采用多元分析确定 <0.05 时妊娠高血压的预测因素。

结果

18 至 41 岁的妇女参与了这项研究,平均年龄为 26.00(SD±4.42),病例组和对照组分别为 25.87(SD±5.02)。在参与者中,21 名(30.4%)病例组和 21 名(15.2%)对照组在分娩后至少发生了一种并发症。病例组和对照组分别有 12 名(17.4%)和 8 名(5.7%)胎儿死亡,而病例组有 15.6%和对照组有 3.6%的胎儿宫内生长迟缓。妇女的孕次 AOR = 0.32 [95% CI (0.12, 0.86)],既往妊娠高血压史 AOR = 22.50 [95% CI (14.95, 16.52)]和教育状况 AOR = 0.32[95% CI (0.12, 0.85)]被确定为妊娠高血压的预测因素。

结论

有既往妊娠高血压史的妇女发生妊娠高血压的风险增加,而≥3 次妊娠和非正规教育状况降低发生妊娠高血压的几率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d8d/8115896/0b614cd22bb7/pone.0250548.g001.jpg

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