Universidade Estadual de Campinas, São Paulo, SP, Brazil.
Faculdade de Medicina de Jundiaí, Jundiaí, SP, Brazil.
Rev Bras Ginecol Obstet. 2021 Apr;43(4):291-296. doi: 10.1055/s-0041-1726056. Epub 2021 May 12.
To evaluate whether continuation rates with the 52-mg levonorgestrel-releasing intrauterine system (LNG-IUS) up to 5 years after placement differed between women using the method exclusively for contraception and those using the device for medical reasons alone.
A retrospective cohort study was conducted in a family planning clinic with 5,034 LNG-IUS users: 4,287 using the method exclusively for contraception and 747 for medical reasons alone. The continuation rate at 1 to 5 years of use was calculated by life table analysis.
Initially, the continuation rate was significantly higher in the contraception group: 85.8 versus 83.4 and 77.4 versus 76.0 per 100 women-years in the 1 and 2 years of use, respectively. There were more discontinuations due to bleeding/spotting in the medical reasons group in the first two years. The discontinuation rate according to reason for use was not significantly different from the third to the fifth year of use. No women discontinued due to amenorrhea in either group.
The continuation rate was significantly higher in the contraception group in the first two years of use. Amenorrhea was not a reason for discontinuation in either group, suggesting that counselling in this respect was adequate. Nevertheless, counselling could perhaps have been better with regards to the expected long period of bleeding and spotting in the first two years after placement.
评估在放置后 5 年内,52 毫克左炔诺孕酮释放宫内节育系统(LNG-IUS)的续用率是否因仅将其用于避孕的女性和仅将其用于医疗原因的女性而有所不同。
在一家计划生育诊所进行了一项回顾性队列研究,共有 5034 名 LNG-IUS 用户:4287 名仅将其用于避孕,747 名仅将其用于医疗原因。通过寿命表分析计算使用 1 至 5 年的续用率。
最初,避孕组的续用率明显更高:使用 1 年和 2 年的续用率分别为每 100 名女性 85.8 和 83.4 与 77.4 和 76.0,而在医疗原因组中,前两年因出血/点滴而停药的情况更多。按使用原因计算的停药率在使用第 3 年到第 5 年之间没有显著差异。两组均无因闭经而停药的女性。
在使用的前两年,避孕组的续用率明显更高。两组均无因闭经而停药,表明在这方面的咨询是充分的。然而,对于放置后前两年预期的长时间出血和点滴,咨询可能还可以做得更好。