CAS Key Laboratory of Environmental Biotechnology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100049, China.
CAS Key Laboratory of Environmental Biotechnology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100049, China.
Chemosphere. 2021 Jul;274:129970. doi: 10.1016/j.chemosphere.2021.129970. Epub 2021 Feb 15.
Nitrification and denitrification are crucial processes in the nitrogen cycle, a vital microbially driven biogeochemical cycle. N-acyl-homoserine lactone (AHL)-mediated quorum sensing (QS) is widespread in bacteria and plays a key role in their physiological status. Recently, there has been an increase in research into how the AHL-mediated QS system is involved in nitrification and denitrification. Consequentially, the AHL-mediated QS system has been considered a promising regulatory approach in nitrogen metabolism processes, with high potential for real-world applications. In this review, the universal presence of QS in nitrifiers and denitrifiers is summarized. Many microorganisms taking part in nitrification and denitrification harbor QS genes, and they may produce AHLs with different chain lengths. The phenotypes and processes affected by QS in real-world applications are also reviewed. In wastewater bioreactors, QS could affect nitrogen metabolism efficiency, granule aggregation, and biofilm formation. Furthermore, methods commonly used to identify the existence and functions of QS, including physiological tests, genetic manipulation and omics analyses are discussed.
硝化和反硝化是氮循环中的关键过程，氮循环是一个重要的微生物驱动的生物地球化学循环。酰高丝氨酸内酯（AHL）介导的群体感应（QS）在细菌中广泛存在，并在其生理状态中发挥关键作用。最近，越来越多的研究关注 AHL 介导的 QS 系统如何参与硝化和反硝化。因此，AHL 介导的 QS 系统被认为是一种很有前途的氮代谢过程的调控方法，具有很高的实际应用潜力。在这篇综述中，总结了 QS 在硝化菌和反硝化菌中的普遍存在。许多参与硝化和反硝化的微生物都携带有 QS 基因，并且它们可能产生不同链长的 AHL。还综述了 QS 在实际应用中对表型和过程的影响。在废水生物反应器中，QS 可能会影响氮代谢效率、颗粒聚集和生物膜形成。此外，还讨论了常用于鉴定 QS 存在和功能的方法，包括生理测试、遗传操作和组学分析。
