Kim Hyun-Ju, Kim Ji Eun, Lee Sang-Hyuk
Department of Psychiatry, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Republic of Korea.
Graduate School of Social Welfare, Yonsei University, Seoul, Republic of Korea.
Psychiatry Investig. 2021 May;18(5):434-442. doi: 10.30773/pi.2020.0425. Epub 2021 May 14.
Anxiety and depression and sociodemographic factors such as age, gender, education level, income, and marital status among people with panic disorder (PD) are associated with functional impairment in the areas of work, social, and family. Although both PD-specific scales such as the Panic Disorder Severity Scale (PDSS) and Anxiety Sensitivity Inventory-Revised (ASI-R) and early trauma have been investigated, their relationship with functional impairment in PD patients has not been clarified.
This study included 267 PD patients. The PDSS, Beck Depression Inventory (BDI), ASI-R, and Early Trauma Inventory were used. Pearson's correlation and multiple linear regression analyses were performed. The Sheehan Disability Scale (SDS) was administered to assess the functional impairment level in PD patients.
Our findings showed that high levels of PDSS, BDI, and ASI-R were significantly correlated with the functional impairment among PD patients. Multiple regression analyses showed that PDSS, BDI, and ASI-R can predict the functional impairment levels, and PDSS and ASI-R were significantly associated with lost and underproductive days in PD patients.
Panic-specific symptoms, depression, and AS are associated with functional impairment level in PD patients. Elevated symptom severity can play a role by affecting productivity and daily responsibilities in PD patients.
惊恐障碍（PD）患者的焦虑、抑郁以及年龄、性别、教育程度、收入和婚姻状况等社会人口学因素与工作、社交和家庭方面的功能损害相关。尽管已经对诸如惊恐障碍严重程度量表（PDSS）和修订版焦虑敏感性量表（ASI-R）等特定于PD的量表以及早期创伤进行了研究，但它们与PD患者功能损害的关系尚未明确。
本研究纳入了267名PD患者。使用了PDSS、贝克抑郁量表（BDI）、ASI-R和早期创伤量表。进行了Pearson相关性分析和多元线性回归分析。采用希恩残疾量表（SDS）评估PD患者的功能损害水平。
我们的研究结果表明，高水平的PDSS、BDI和ASI-R与PD患者的功能损害显著相关。多元回归分析表明，PDSS、BDI和ASI-R可以预测功能损害水平，并且PDSS和ASI-R与PD患者的误工和工作效率低下天数显著相关。
惊恐特异性症状、抑郁和焦虑敏感性与PD患者的功能损害水平相关。症状严重程度的升高可通过影响PD患者的工作效率和日常责任发挥作用。
