O'Neill Francis, Kobylecki Christopher, Carrasco Roberto, Hu Michele T, Grosset Donald, Silverdale Monty
Oral Surgery, Institute of Clinical Sciences, University of Liverpool, Liverpool, United Kingdom.
Department of Neurology, Salford Royal NHS Foundation Trust, Manchester, United Kingdom.
Pain Rep. 2021 Apr 13;6(1):e923. doi: 10.1097/PR9.0000000000000923. eCollection 2021.
Several studies have reported that some types of orofacial pain are more common in patients with Parkinson disease (PD) than the general population.
In this study, we aimed to investigate the prevalence of self-reported orofacial pain in a larger group of patients with PD than has been previously studied.
We analysed data from 1916 participants with PD in a cross-sectional study recruited to the UK Parkinson's Pain Study who had detailed assessments of pain, motor, and nonmotor symptoms. The King's Parkinson's Pain scale was used to quantify different subtypes of pain.
A total of 139 (7.3%) patients reported the presence of some form of orofacial pain. Burning mouth syndrome was reported in 32 (1.7%), whereas chewing pain was found in 38 (2.0%) and grinding pain in 78 (4.0%). Orofacial pain was significantly more common in females (10.4%) than males (5.9%). Multiple logistic regression analysis showed a significant association between orofacial pain and pain severity, neuropathic pain, and oral motor and nonmotor dysfunction.
In our study, population cohort of early patients with PD found prevalence of orofacial pain conditions similar to that in the general population.
多项研究报告称,某些类型的口面部疼痛在帕金森病(PD)患者中比在普通人群中更为常见。
在本研究中,我们旨在调查比先前研究的更大规模的PD患者群体中自我报告的口面部疼痛的患病率。
我们在一项横断面研究中分析了来自1916名PD参与者的数据,这些参与者被招募到英国帕金森疼痛研究中,对疼痛、运动和非运动症状进行了详细评估。使用国王帕金森疼痛量表来量化不同类型的疼痛。
共有139名(7.3%)患者报告存在某种形式的口面部疼痛。32名(1.7%)患者报告有灼口综合征,38名(2.0%)患者有咀嚼疼痛,78名(4.0%)患者有磨牙疼痛。口面部疼痛在女性(10.4%)中比男性(5.9%)更常见。多元逻辑回归分析显示口面部疼痛与疼痛严重程度、神经性疼痛以及口腔运动和非运动功能障碍之间存在显著关联。
在我们的研究中,早期PD患者群体中口面部疼痛状况的患病率与普通人群相似。