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33MHz 超高频超声在腋臭患者腋下汗腺评估中的应用。

The use of 33 MHz ultra-high-frequency ultrasonography for the evaluation of sweat glands in the axilla with osmidrosis.

机构信息

Department of Human Morphology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama, Japan.

Department of Plastic and Reconstructive Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama, Japan.

出版信息

PLoS One. 2021 May 13;16(5):e0251600. doi: 10.1371/journal.pone.0251600. eCollection 2021.

DOI:10.1371/journal.pone.0251600
PMID:33984036
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8118561/
Abstract

BACKGROUND

This study aimed to assess the use of 33 MHz ultra-high-frequency ultrasonography (33MHz-UHFUS) for evaluating axillary sweat glands with osmidrosis in comparison with histological techniques. Axillary osmidrosis is a common problem in Asian societies, and the number and size of apocrine sweat glands have a strong relationship with osmidrosis severity. Currently, there are no methods to evaluate sweat gland distribution non-invasively.

METHODS

In this study, 35 skin specimens from 10 fresh human cadavers without osmidrosis and retrospective ultrasonographic images from 20 patients with osmidrosis were used. Skin specimens were embedded in paraffin, thinly sliced, and finally stained with hematoxylin and eosin. Histologically, the apocrine and eccrine glands were evaluated, and the top and bottom depths of follicles were measured from the skin surface. In 33 MHz ultrasonography images, the depths of sweat glands were measured, and the mean grey value was calculated using Image J.

RESULTS

Compared to histological data, 33MHz-UHFUS could be used to identify sweat glands as a hyperechoic structure between the dermis and fat layer. Furthermore, it could evaluate sweat gland distribution but could not distinguish between types of sweat glands.

CONCLUSIONS

The distribution of sweat glands in the axilla can be non-invasively evaluated via 33MHz-UHFUS.

摘要

背景

本研究旨在评估 33MHz 超高频超声（33MHz-UHFUS）在评估腋臭腋部汗腺中的应用，并与组织学技术进行比较。腋臭在亚洲社会中较为常见，大汗腺的数量和大小与腋臭的严重程度密切相关。目前，尚无非侵入性评估汗腺分布的方法。

方法

本研究使用了 10 例无腋臭的新鲜人体尸体的 35 个皮肤标本和 20 例腋臭患者的回顾性超声图像。皮肤标本包埋于石蜡中，薄切片，最后用苏木精和伊红染色。组织学上评估了顶泌腺和小汗腺，并从皮肤表面测量了毛囊的顶部和底部深度。在 33MHz 超声图像中，测量了汗腺的深度，并使用 Image J 计算了平均灰度值。

结果

与组织学数据相比，33MHz-UHFUS 可用于识别真皮和脂肪层之间的高回声结构作为汗腺。此外，它可以评估汗腺的分布，但不能区分汗腺类型。

结论

33MHz-UHFUS 可用于非侵入性评估腋窝中的汗腺分布。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32f9/8118561/69aba29ce6bd/pone.0251600.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32f9/8118561/e071ff3667ec/pone.0251600.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32f9/8118561/5343277e2c3e/pone.0251600.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32f9/8118561/226c1e97779c/pone.0251600.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32f9/8118561/e096103f74e1/pone.0251600.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32f9/8118561/69aba29ce6bd/pone.0251600.g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32f9/8118561/e071ff3667ec/pone.0251600.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32f9/8118561/5343277e2c3e/pone.0251600.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32f9/8118561/226c1e97779c/pone.0251600.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32f9/8118561/e096103f74e1/pone.0251600.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32f9/8118561/69aba29ce6bd/pone.0251600.g005.jpg

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